日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Codelivery of TGFβ and Cox2 siRNA inhibits HCC by promoting T-cell penetration into the tumor and improves response to Immune Checkpoint Inhibitors

TGFβ 和 Cox2 siRNA 的共同递送可通过促进 T 细胞渗透到肿瘤中来抑制 HCC,并改善对免疫检查点抑制剂的反应

Wookhyun Kim, Zhou Ye, Vera Simonenko, Aashirwad Shahi, Asra Malikzay, Steven Z Long, John J Xu, Alan Lu, Jau-Hau Horng, Chang-Ru Wu, Pei-Jer Chen, Patrick Y Lu, David M Evans

A novel siRNA-gemcitabine construct as a potential therapeutic for treatment of pancreatic cancer

一种新型 siRNA-吉西他滨构建体可作为治疗胰腺癌的潜在疗法

Vera Simonenko, Xiaoyong Lu, Eric Roesch, Daniel Mutisya, Chunbo Shao, Qian Sun, Athéna Patterson-Orazem, Marcus McNair, Aranganathan Shanmuganathan, Patrick Lu, David M Evans

Soft-surface grasping: radular opening in Aplysia californica

软表面抓握:加州海兔的齿状开口

Catherine E Kehl, Joey Wu, Sisi Lu, David M Neustadter, Richard F Drushel, Rebekah K Smoldt, Hillel J Chiel

KMT2D/MLL2 inactivation is associated with recurrence in adult-type granulosa cell tumors of the ovary

KMT2D/MLL2 失活与成人型卵巢颗粒细胞瘤复发相关

R Tyler Hillman, Joseph Celestino, Christopher Terranova, Hannah C Beird, Curtis Gumbs, Latasha Little, Tri Nguyen, Rebecca Thornton, Samantha Tippen, Jianhua Zhang, Karen H Lu, David M Gershenson, Kunal Rai, Russell R Broaddus, P Andrew Futreal

Severe Iron Metabolism Defects in Mice With Double Knockout of the Multicopper Ferroxidases Hephaestin and Ceruloplasmin

多铜氧化铁酶 Hephaestin 和铜蓝蛋白双敲除小鼠出现严重铁代谢缺陷

Brie K Fuqua, Yan Lu, David M Frazer, Deepak Darshan, Sarah J Wilkins, Linda Dunn, Alex V Loguinov, Scott C Kogan, Pavle Matak, Huijun Chen, Joshua L Dunaief, Chris D Vulpe, Gregory J Anderson

Baicalein upregulates DDIT4 expression which mediates mTOR inhibition and growth inhibition in cancer cells

黄芩苷上调DDIT4表达,从而介导mTOR抑制和癌细胞生长抑制。

Wang, Yujun; Han, Ernest; Xing, Quanhua; Yan, Jin; Arrington, Amanda; Wang, Charles; Tully, Dylan; Kowolik, Claudia M; Lu, David M; Frankel, Paul H; Zhai, Jing; Wen, Wei; Horne, David; Yip, M L Richard; Yim, John H

Intrahepatic activation of naive CD4+ T cells by liver-resident phagocytic cells

肝内驻留吞噬细胞对幼稚 CD4+ T 细胞的激活

Szun S Tay, Yik Chun Wong, Ben Roediger, Frederic Sierro, Bo Lu, David M McDonald, Claire M McGuffog, Nicholas J Meyer, Ian E Alexander, Ian A Parish, William R Heath, Wolfgang Weninger, G Alex Bishop, Jennifer R Gamble, Geoffrey W McCaughan, Patrick Bertolino, David G Bowen

Acid sphingomyelinase plays a key role in palmitic acid-amplified inflammatory signaling triggered by lipopolysaccharide at low concentrations in macrophages

酸性鞘磷脂酶在巨噬细胞中低浓度脂多糖引发的棕榈酸放大炎症信号中起关键作用

Junfei Jin, Xiaoming Zhang, Zhongyang Lu, David M Perry, Yanchun Li, Sarah Brice Russo, L Ashley Cowart, Yusuf A Hannun, Yan Huang

An alternative Kaposi's sarcoma-associated herpesvirus replication program triggered by host cell apoptosis

宿主细胞凋亡引发的另一种卡波西肉瘤相关疱疹病毒复制程序

Alka Prasad, Michael Lu, David M Lukac, Steven L Zeichner

Identification of a natural compound by cell-based screening that enhances interferon regulatory factor-1 activity and causes tumor suppression.

通过基于细胞的筛选鉴定出一种天然化合物,该化合物可增强干扰素调节因子-1的活性并抑制肿瘤生长

Gao Jinbo, Wang Yujun, Xing Quanhua, Yan Jin, Senthil Maheswari, Akmal Yasir, Kowolik Claudia M, Kang Julia, Lu David M, Zhao Ming, Lin Zhixiu, Cheng Christopher H K, Yip M L Richard, Yim John H