日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Sleep deprivation disrupts lacrimal gland homeostasis via hypothalamic-pituitary-adrenal axis and gut dysbiosis in mice.

睡眠剥夺会通过下丘脑-垂体-肾上腺轴和肠道菌群失调破坏小鼠的泪腺稳态。

期刊:Communications Biology
影响因子:5.1
doi:10.1038/s42003-026-09657-0
Huang Shenzhen, Yu Shufan, Zhang Wenxiao, Qi Di, Pei Xiaoting, Lu Dingli, Ba Mengru, Xuan Shuting, Huang Duliurui, Yang Jingwen, Li Zhijie
微生物学
肠道菌群
神经科学
免疫/内分泌
发表日期：2026
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Circadian disruption and ROS-NLRP3 signaling mediate sleep deprivation-enhanced silica nanoparticle toxicity in lacrimal glands.

昼夜节律紊乱和 ROS-NLRP3 信号传导介导睡眠剥夺增强的二氧化硅纳米颗粒对泪腺的毒性

期刊:Journal of Nanobiotechnology
影响因子:12.6
doi:10.1186/s12951-025-03630-5
Zhang Wenxiao, Qi Di, Pei Xiaoting, Lu Dingli, Ba Mengru, Xuan Shuting, Huang Duliurui, Yang Tingting, Yang Jingwen, Li Zhijie, Huang Shenzhen
信号转导
发表日期：2025
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Leptin Receptor Deficiency-Associated Diabetes Disrupts Lacrimal Gland Circadian Rhythms and Contributes to Dry Eye Syndrome

瘦素受体缺乏相关性糖尿病会扰乱泪腺昼夜节律，并导致干眼症。

期刊:Investigative Ophthalmology & Visual Science
影响因子:4.7
doi:10.1167/iovs.66.1.19
Pei, Xiaoting; Ba, Mengru; Yang, Tingting; Xuan, Shuting; Huang, Duliurui; Qi, Di; Lu, Dingli; Huang, Shenzhen; Li, Zhijie
干眼症
糖尿病
信号转导
代谢
发表日期：2025
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Hypoxia Alters Corneal Circadian Rhythms and Disrupts Epithelial, Neural, and Immune Balance

缺氧会改变角膜昼夜节律并破坏上皮、神经和免疫平衡。

期刊:Investigative Ophthalmology & Visual Science
影响因子:4.7
doi:10.1167/iovs.66.14.5
Liu, Jiangman; Jing, Yuxin; Wu, Jiaxin; Lu, Dingli; Li, Zhijie
免疫/内分泌
发表日期：2025
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Plin2 Coordinates Immune and Metabolic Reprogramming in Lacrimal Gland Aging

Plin2 协调泪腺衰老过程中的免疫和代谢重编程

期刊:Investigative Ophthalmology & Visual Science
影响因子:4.7
doi:10.1167/iovs.66.6.79
Pei, Xiaoting; Xuan, Shuting; Yang, Jingwen; Ba, Mengru; Yang, Tingting; Huang, Duliurui; Qi, Di; Lu, Dingli; Huang, Shenzhen; Li, Zhijie
代谢
代谢重编程
衰老
免疫/内分泌
发表日期：2025
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Stress-Induced Disruption of Circadian and Neuroimmune Networks in Lacrimal Glands Drives Dry Eye Pathogenesis

应激诱导的泪腺昼夜节律和神经免疫网络紊乱驱动干眼症的发病机制

期刊:Investigative Ophthalmology & Visual Science
影响因子:4.7
doi:10.1167/iovs.66.15.53
Ba, Mengru; Huang, Duliurui; Yang, Tingting; Xuan, Shuting; Zhang, Wenxiao; Qi, Di; Pei, Xiaoting; Lu, Dingli; Huang, Shenzhen; Yang, Jingwen; Liu, Xiaohui; Li, Zhijie
干眼症
免疫/内分泌
发表日期：2025
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Chronic Restraint Stress Misaligns Corneal Clock via β-Adrenergic and Glucocorticoid Signaling, Altering Epithelial, Neural, Immune, Metabolic States

慢性束缚应激通过β-肾上腺素能和糖皮质激素信号通路扰乱角膜生物钟，改变上皮、神经、免疫和代谢状态

期刊:Investigative Ophthalmology & Visual Science
影响因子:4.7
doi:10.1167/iovs.66.15.50
Xuan, Shuting; Yang, Tingting; Ba, Mengru; Zhang, Wenxiao; Yang, Jingwen; Pei, Xiaoting; Qi, Di; Lu, Dingli; Huang, Shenzhen; Li, Zhijie
代谢
信号转导
免疫/内分泌
发表日期：2025
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High-fat intake reshapes the circadian transcriptome profile and metabolism in murine meibomian glands

高脂肪摄入会改变小鼠睑板腺的昼夜节律转录组谱和代谢

期刊:Frontiers in Nutrition
影响因子:5.1
doi:10.3389/fnut.2023.1146916
Zou, Sen; Liu, Jiangman; Si, Hongli; Huang, Duliurui; Qi, Di; Pei, Xiaoting; Lu, Dingli; Huang, Shenzhen; Li, Zhijie
代谢
发表日期：2023
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High-Fat Nutritional Challenge Reshapes Circadian Signatures in Murine Extraorbital Lacrimal Glands

高脂营养挑战重塑小鼠眶外泪腺的昼夜节律特征。

期刊:Investigative Ophthalmology & Visual Science
影响因子:4.7
doi:10.1167/iovs.63.5.23
Zou, Sen; Jiao, Xinwei; Liu, Jiangman; Qi, Di; Pei, Xiaoting; Lu, Dingli; Huang, Shenzhen; Li, Zhijie
发表日期：2022
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Recent advances in modulators of circadian rhythms: an update and perspective

昼夜节律调节剂的最新进展：现状与展望

期刊:Journal of Enzyme Inhibition and Medicinal Chemistry
影响因子:5.4
doi:10.1080/14756366.2020.1772249
Huang, Shenzhen; Jiao, Xinwei; Lu, Dingli; Pei, Xiaoting; Qi, Di; Li, Zhijie
发表日期：2020
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