日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The Challenges and Prospects of p53-Based Therapies in Ovarian Cancer

p53靶向疗法在卵巢癌治疗中的挑战与前景

Wallis, Bryce; Bowman, Katherine Redd; Lu, Phong; Lim, Carol S

p53-Bad* Fusion Gene Therapy Induces Apoptosis In Vitro and Reduces Zebrafish Tumor Burden in Hepatocellular Carcinoma

p53-Bad*融合基因疗法在体外诱导细胞凋亡并降低斑马鱼肝细胞癌的肿瘤负荷

Bowman, Katherine E Redd; Ahne, Lisa; O'Brien, Liam; Vander Mause, Erica R; Lu, Phong; Wallis, Bryce; Evason, Kimberley J; Lim, Carol S

p53-Bad* in a Hepatocellular Carcinoma Mouse Model

p53-Bad* 在肝细胞癌小鼠模型中的作用

Bowman, Katherine Redd; Lu, Phong; Lim, Carol

p53-Bad: A Novel Tumor Suppressor/Proapoptotic Factor Hybrid Directed to the Mitochondria for Ovarian Cancer Gene Therapy

p53-Bad:一种靶向线粒体的新型肿瘤抑制/促凋亡因子杂合体,用于卵巢癌基因治疗

Lu, Phong; Redd Bowman, Katherine E; Brown, Sarah M; Joklik-Mcleod, Madeline; Vander Mause, Erica R; Nguyen, Han T N; Lim, Carol S

Mitochondrially targeted p53 or DBD subdomain is superior to wild type p53 in ovarian cancer cells even with strong dominant negative mutant p53.

即使在卵巢癌细胞中存在强显性负突变 p53,线粒体靶向的 p53 或 DBD 亚结构域也优于野生型 p53

Lu Phong, Vander Mause Erica R, Redd Bowman Katherine E, Brown Sarah M, Ahne Lisa, Lim Carol S