日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Tumor-associated CD19(+) macrophages induce immunosuppressive microenvironment in hepatocellular carcinoma

肿瘤相关CD19(+)巨噬细胞在肝细胞癌中诱导免疫抑制性微环境

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-026-69638-z
Wang, Junli; Cao, Wanyue; Huang, Jinyan; Zhou, Yu; Zheng, Rujia; Lou, Yu; Yang, Jiaqi; Yan, Jiawei; Tang, Jianghui; Ye, Mao; Hong, Zhengtao; Wu, Jiangchao; Ding, Haonan; Zhang, Yuquan; Sheng, Jianpeng; Lu, Xinjiang; Xu, Pinglong; Lu, Xiongbin; Bai, Xueli; Liang, Tingbo; Zhang, Qi
巨噬细胞
肿瘤
肿瘤免疫
巨噬细胞
细胞生物学
CD19
免疫/内分泌
发表日期：2026
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Retraction for Atractylenolide I enhances responsiveness to immune checkpoint blockade therapy by activating tumor antigen presentation

撤回研究表明，白术内酯I通过激活肿瘤抗原呈递增强对免疫检查点阻断疗法的反应。

期刊:Journal of Clinical Investigation
影响因子:13.6
doi:10.1172/JCI202473
Xu, Hanchen; Van der Jeught, Kevin; Zhou, Zhuolong; Zhang, Lu; Yu, Tao; Sun, Yifan; Li, Yujing; Wan, Changlin; So, Ka Man; Liu, Degang; Frieden, Michael; Fang, Yuanzhang; Mosley, Amber L; He, Xiaoming; Zhang, Xinna; Sandusky, George E; Liu, Yunlong; Meroueh, Samy O; Zhang, Chi; Wijeratne, Aruna B; Huang, Cheng; Ji, Guang; Lu, Xiongbin
肿瘤
肿瘤免疫
免疫/内分泌
发表日期：2026
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Retraction for Somatic mutation of the cohesin complex subunit confers therapeutic vulnerabilities in cancer

撤回关于黏连蛋白复合物亚基体细胞突变导致癌症治疗脆弱性的研究

期刊:Journal of Clinical Investigation
影响因子:13.6
doi:10.1172/JCI202472
Liu, Yunhua; Xu, Hanchen; Van der Jeught, Kevin; Li, Yujing; Liu, Sheng; Zhang, Lu; Fang, Yuanzhang; Zhang, Xinna; Radovich, Milan; Schneider, Bryan P; He, Xiaoming; Huang, Cheng; Zhang, Chi; Wan, Jun; Ji, Guang; Lu, Xiongbin
细胞生物学
肿瘤
肿瘤免疫
发表日期：2026
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Reprogramming intratumoral T(reg) cells by morpholino-mediated splicing of FOXP3 for cancer immunotherapy

利用吗啉代寡核苷酸介导的FOXP3剪接重编程肿瘤内T(reg)细胞用于癌症免疫治疗

期刊:Science Immunology
影响因子:16.3
doi:10.1126/sciimmunol.adr9933
Li, Yujing; Singh, Naresh; Dong, Chuanpeng; Sharma, Samantha; Zhou, Zhuolong; Du, Jianguang; Haouili, Maya; Jiao, Yile; Hopewell, Emily; Liu, Yunlong; Opyrchal, Mateusz; Zhang, Xinna; Zhou, Baohua; Lu, Xiongbin
肿瘤
肿瘤免疫
FOXP3
细胞生物学
免疫/内分泌
发表日期：2025
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Targeting spermine metabolism to overcome immunotherapy resistance in pancreatic cancer.

靶向亚精胺代谢以克服胰腺癌的免疫治疗耐药性

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-63146-2
Yang Hanshen, Zhang Xiaozhen, Zhang Sirui, Yang Yanqing, Chen Yan, Jiang Yangwei, Lu Qingsong, Liu Lingyue, Lao Mengyi, Du Weiran, Sun Kang, He Lihong, Shi Jiatao, Liu Xinyuan, Song Jinyuan, Lu Na, Huang Junming, Huang Jinyan, Zhou Ruhong, Lu Xiongbin, Liang Tingbo, Bai Xueli
代谢
胰腺癌
发表日期：2025
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Elevated protein lactylation promotes immunosuppressive microenvironment and therapeutic resistance in pancreatic ductal adenocarcinoma

胰腺导管腺癌中蛋白质乳酸化水平升高会促进免疫抑制微环境的形成和治疗耐药性。

期刊:Journal of Clinical Investigation
影响因子:13.6
doi:10.1172/JCI187024
Sun, Kang; Zhang, Xiaozhen; Shi, Jiatao; Huang, Jinyan; Wang, Sicheng; Li, Xiang; Lin, Haixiang; Zhao, Danyang; Ye, Mao; Zhang, Sirui; Qiu, Li; Yang, Minqi; Liao, Chuyang; He, Lihong; Lao, Mengyi; Song, Jinyuan; Lu, Na; Ji, Yongtao; Yang, Hanshen; Liu, Lingyue; Liu, Xinyuan; Chen, Yan; Yao, Shicheng; Xu, Qianhe; Lin, Jieru; Mao, Yan; Zhou, Jingxing; Zhi, Xiao; Sun, Ke; Lu, Xiongbin; Bai, Xueli; Liang, Tingbo
肿瘤
肿瘤免疫
治疗耐药
乳酸化
免疫/内分泌
发表日期：2025
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STK11 coordinates IL-4 signaling with metabolic reprogramming to control M2 macrophage polarization and antitumor immunity

STK11通过协调IL-4信号通路与代谢重编程来控制M2巨噬细胞极化和抗肿瘤免疫。

期刊:Science Advances
影响因子:12.5
doi:10.1126/sciadv.adx5495
Yang, Jing; Singh, Naresh; Xu, Chengxian; Kong, Dehui; Sharma, Samantha; Liu, Sheng; Lechner, Joseph; Lkhagva, Ankhbayar; Tan, Haiyan; Wu, Zhiping; Richer, Martin J; Zang, Yong; Huang, Xiumei; Kapur, Reuben; Wan, Jun; High, Anthony A; Zhang, Xinna; Wang, Xusheng; Lu, Xiongbin; Yang, Kai
巨噬细胞
肿瘤
肿瘤免疫
巨噬细胞
信号转导
代谢
代谢重编程
细胞生物学
IL-4
STK11
免疫/内分泌
发表日期：2025
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Sphingolipid synthesis in tumor-associated macrophages confers immunotherapy resistance in hepatocellular carcinoma.

肿瘤相关巨噬细胞中的鞘脂合成赋予肝细胞癌免疫治疗耐药性

期刊:Science Advances
影响因子:12.5
doi:10.1126/sciadv.adv0558
Zhang Xiaozhen, Lao Mengyi, Sun Kang, Yang Hanshen, He Lihong, Liu Xinyuan, Liu Linyue, Zhang Sirui, Guo Chengxiang, Wang Sicheng, Shi Jiatao, Zhang Xiaoyu, Xu Daqian, Lu Xiongbin, Bai Xueli, Liang Tingbo
细胞生物学
肿瘤
巨噬细胞
发表日期：2025
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A physics informed neural network approach to quantify antigen presentation activities at single cell level using omics data

利用物理学原理指导的神经网络方法，结合组学数据，量化单细胞水平的抗原呈递活性。

期刊:
影响因子:
doi:10.21203/rs.3.rs-5629379/v1
Zhang, Chi; Wang, Jia; Dang, Pengtao; Wei, Yuhui; Wang, Xiao; Brothwell, Julie; Sun, Yifan; Zhu, Haiqi; So, Kaman; Liu, Jing; Wang, Yijie; Lu, Xiongbin; Spinola, Stanley; Zhang, Xinna; Cao, Sha
细胞生物学
单细胞
发表日期：2025
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Retraction of "Overcoming Ovarian Cancer Drug Resistance with a Cold Responsive Nanomaterial"

撤稿声明：《利用冷响应纳米材料克服卵巢癌耐药性》

期刊:ACS Central Science
影响因子:10.4
doi:10.1021/acscentsci.3c00335
Wang, Hai; Agarwal, Pranay; Zhao, Gang; Ji, Guang; Jewell, Christopher M; Fisher, John P; Lu, Xiongbin; He, Xiaoming
肿瘤
肿瘤免疫
卵巢癌
发表日期：2023
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