日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

High-resolution deep mutational scanning of the melanocortin-4 receptor enables target characterization for drug discovery

对黑皮质素-4受体进行高分辨率深度突变扫描,能够实现药物发现的靶点表征。

Howard, Conor J; Abell, Nathan S; Osuna, Beatriz A; Jones, Eric M; Chan, Leon Y; Chan, Henry; Artis, Dean R; Asfaha, Jonathan B; Bloom, Joshua S; Cooper, Aaron R; Liao, Andrew; Mahdavi, Eden; Mohammed, Nabil; Su, Alan L; Uribe, Giselle A; Kosuri, Sriram; Dickel, Diane E; Lubock, Nathan B

RHO-Associated Retinitis Pigmentosa: Genetics, Phenotype, Natural History, Functional Assays, and Animal Model - In Preparation for Clinical Trials

RHO相关性视网膜色素变性:遗传学、表型、自然史、功能分析和动物模型——为临床试验做准备

Daich Varela, Malena; Romo-Aguas, Juan Carlos; Guarascio, Rosellina; Ziaka, Kalliopi; Aguila, Monica; Hau, Kwan-Leong; Li, Yumei; Chen, Rui; Kalitzeos, Angelos; Robson, Anthony G; Baker, Rebecca A; Mahroo, Omar A; Webster, Andrew R; Chan, Henry; Lubock, Nathan B; Albert, Matthew L; Cheetham, Michael E; Michaelides, Michel

A multiplexed bacterial two-hybrid for rapid characterization of protein-protein interactions and iterative protein design

一种用于快速表征蛋白质-蛋白质相互作用和迭代蛋白质设计的多重细菌双杂交系统

W Clifford Boldridge # ,Ajasja Ljubetič # ,Hwangbeom Kim ,Nathan Lubock ,Dániel Szilágyi ,Jonathan Lee ,Andrej Brodnik ,Roman Jerala ,Sriram Kosuri

Massively scaled-up testing for SARS-CoV-2 RNA via next-generation sequencing of pooled and barcoded nasal and saliva samples

通过对汇集并贴有条形码的鼻腔和唾液样本进行新一代测序,大规模扩大 SARS-CoV-2 RNA 检测

Joshua S Bloom, Laila Sathe, Chetan Munugala, Eric M Jones, Molly Gasperini, Nathan B Lubock, Fauna Yarza, Erin M Thompson, Kyle M Kovary, Jimin Park, Dawn Marquette, Stephania Kay, Mark Lucas, TreQuan Love, A Sina Booeshaghi, Oliver F Brandenberg, Longhua Guo, James Boocock, Myles Hochman, Scott W

Swab-Seq: A high-throughput platform for massively scaled up SARS-CoV-2 testing

Swab-Seq:用于大规模 SARS-CoV-2 检测的高通量平台

Joshua S Bloom, Laila Sathe, Chetan Munugala, Eric M Jones, Molly Gasperini, Nathan B Lubock, Fauna Yarza, Erin M Thompson, Kyle M Kovary, Jimin Park, Dawn Marquette, Stephania Kay, Mark Lucas, TreQuan Love, A Sina Booeshaghi, Oliver F Brandenberg, Longhua Guo, James Boocock, Myles Hochman, Scott W

DropSynth 2.0: high-fidelity multiplexed gene synthesis in emulsions

DropSynth 2.0:乳液中高保真多重基因合成

Angus M Sidore, Calin Plesa, Joyce A Samson, Nathan B Lubock, Sriram Kosuri

Structural and functional characterization of G protein-coupled receptors with deep mutational scanning

利用深度突变扫描对G蛋白偶联受体进行结构和功能表征

Eric M Jones # ,Nathan B Lubock # ,A J Venkatakrishnan ,Jeffrey Wang ,Alex M Tseng ,Joseph M Paggi ,Naomi R Latorraca ,Daniel Cancilla ,Megan Satyadi ,Jessica E Davis ,M Madan Babu ,Ron O Dror ,Sriram Kosuri

Reliable and accurate diagnostics from highly multiplexed sequencing assays

利用高通量测序检测进行可靠、准确的诊断

Booeshaghi, A Sina; Lubock, Nathan B; Cooper, Aaron R; Simpkins, Scott W; Bloom, Joshua S; Gehring, Jase; Luebbert, Laura; Kosuri, Sri; Pachter, Lior

A Scalable, Multiplexed Assay for Decoding GPCR-Ligand Interactions with RNA Sequencing

一种可扩展的、多重检测方法,用于通过 RNA 测序解码 GPCR-配体相互作用

Eric M Jones, Rishi Jajoo, Daniel Cancilla, Nathan B Lubock, Jeffrey Wang, Megan Satyadi, Rockie Chong, Claire de March, Joshua S Bloom, Hiroaki Matsunami, Sriram Kosuri

Multiplexed gene synthesis in emulsions for exploring protein functional landscapes

利用乳液中的多重基因合成来探索蛋白质功能图谱

Plesa, Calin; Sidore, Angus M; Lubock, Nathan B; Zhang, Di; Kosuri, Sriram