日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Human liver-derived organoids recapitulate Oropouche virus infection and manifestation, enabling antiviral drug discovery

人肝源性类器官能够重现奥罗普切病毒的感染和临床表现，从而有助于抗病毒药物的研发。

期刊:Cell Reports Medicine
影响因子:10.6
doi:10.1016/j.xcrm.2026.102646
Li, Jiajing; Wang, Xin; Ding, Yibo; Qin, Fang; de Lima, Shirlene T S; Papamichail, Lito; Schraauwen, Rick; Forato, Julia; Claro, Ingra M; Hua, Xinyi; Simões Mello, Leda M; Offermans, Dewy Mae; Verstegen, Monique M A; Boter, Marjan; Peppelenbosch, Maikel P; Barbiero, Anna; Pagani, Elisabetta; Janssen, Harry L A; Telmos Silva, José A; Dos Santos, Magnun N N; Pincinato, Eder C; Proenca-Modena, José Luiz; Li, Pengfei; Anas, Adam A; van der Laan, Luc J W; Castilletti, Concetta; Oude Munnink, Bas B; de Souza, William M; Wang, Wenshi; Pan, Qiuwei
炎症/感染
Human
3D/类器官
微生物学
发表日期：2026
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Interpretable and granular video-based quantification of motor characteristics from the finger-tapping test in Parkinson's disease

基于视频的帕金森病手指敲击测试运动特征的可解释和精细量化

期刊:Npj Parkinsons Disease
影响因子:8.2
doi:10.1038/s41531-026-01307-w
Zarrat Ehsan, Tahereh; Tangermann, Michael; Güçlütürk, Yağmur; Shin, SooYoon; Ho, King Chung; Bloem, Bastiaan R; Evers, Luc J W
帕金森
神经科学
发表日期：2026
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Functional characterization of BAP1 mutations in genome edited cholangiocarcinoma organoids: Role in cell death and drug responses

基因组编辑胆管癌类器官中BAP1突变的功能表征：在细胞死亡和药物反应中的作用

期刊:iScience
影响因子:4.6
doi:10.1016/j.isci.2026.114982.
Wunan Mi,Shaojun Shi,Imre F Schene,Indi P Joore,Henk P Roest,Sabine A Fuchs,Luc J W van der Laan,Monique M A Verstegen
胆管癌
细胞生物学
肿瘤
BAP1
3D/类器官
发表日期：2026
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6-mercaptopurine and tofacitinib alter microbial protein expression but not composition in fecal microbiota incubations from Crohn's disease patients

6-巯基嘌呤和托法替尼会改变克罗恩病患者粪便微生物群培养物中微生物蛋白的表达，但不会改变其组成。

期刊:BMC Biology
影响因子:4.5
doi:10.1186/s12915-026-02569-9
Becker, Heike E F; Mohren, Ronny; Le, N Giang; Derijks, Luc J J; Jonkers, Daisy M A E; Penders, John
微生物学
克罗恩病
发表日期：2026
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Beyond Decellularization: Remnant Mitochondrial DNA Can Act as Hidden Damage-Associated Molecular Pattern.

超越脱细胞化：残留的线粒体DNA可作为隐藏的损伤相关分子模式。

期刊:Bioengineering-Basel
影响因子:3.8
doi:10.3390/bioengineering13020193
van Hengel Elena V A, Liu Kuan, Roest Henk P, Willemse Jorke, Ober-Vliegen Kimberley, Teurlings Selina M W, Jonge Jeroen de, Verstegen Monique M A, van der Laan Luc J W
细胞生物学
线粒体
发表日期：2026
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Comment on Catanzaro et al. Risk Factors for Recurrence of Primary Sclerosing Cholangitis after Liver Transplantation: Single-Center Data. J. Pers. Med. 2024, 14, 222

对 Catanzaro 等人发表的《肝移植后原发性硬化性胆管炎复发的危险因素：单中心数据》（J. Pers. Med. 2024, 14, 222）一文的评论

期刊:Journal of Personalized Medicine
影响因子:3
doi:10.3390/jpm16010054
Mammadov, Ruslan A; Roest, Henk P; Peppelenbosch, Maikel P; van der Laan, Luc J W
发表日期：2026
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Frequency and mutual associations of knee osteoarthritis features on ultrasound imaging in recent-onset symptomatic knee osteoarthritis patients: A cross-sectional analysis in a convenience sample of Dutch patients

近期发病症状性膝骨关节炎患者超声成像中膝骨关节炎特征的发生频率及其相互关联：一项针对荷兰患者便利样本的横断面分析

期刊:Osteoarthritis and Cartilage Open
影响因子:2.8
doi:10.1016/j.ocarto.2025.100736
Straetemans, Lianne; Verbruggen, Joost; Heijnens, Luc J M; Cals, Jochen W L; de Korte, Chris L; van den Heuvel, Thomas L A; Ottenheijm, Ramon P G
关节炎
发表日期：2026
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Three-year patient-reported outcomes of the BOOG 2013-08 RCT evaluating omission of sentinel lymph node biopsy in early-stage breast cancer patients treated with breast conserving surgery: Impact of personality traits on health-related quality of life

BOOG 2013-08 RCT 的三年患者报告结局：评估早期乳腺癌患者接受保乳手术后省略前哨淋巴结活检的效果：人格特质对健康相关生活质量的影响

期刊:British Journal of Surgery
影响因子:8.8
doi:10.1093/bjs/znaf031
Wintraecken, Veerle M; van Roozendaal, Lori M; Simons, Janine M; de Vries, Jolanda; van Kuijk, Sander M J; Vane, Marissa L G; van Dalen, Thijs; Sackey, Helena; van der Hage, Jos A; Strobbe, Luc J A; Linn, Sabine C; Lobbes, Marc B I; Poortmans, Philip M P; Tjan-Heijnen, Vivianne C G; van de Vijver, Koen K B T; Westenberg, Helen H; Dirksen, Carmen D; de Wilt, Johan H W; Boersma, Liesbeth J; Smidt, Marjolein L
肿瘤
肿瘤免疫
乳腺癌
发表日期：2025
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Lymphoma-on-chip model reveals that lymph node stromal cells promote diffuse large B-cell lymphoma survival and migration

芯片淋巴瘤模型揭示淋巴结基质细胞促进弥漫性大B细胞淋巴瘤的存活和迁移

期刊:Materials Today Bio
影响因子:8.7
doi:10.1016/j.mtbio.2025.101544
Mohammad Jouybar ，Aleksandra M Mikula ，Nanouk Zuidmeer ，Tanja Konijn ，A Vera de Jonge ，Henk P Roest ，Tuna Mutis ，Luc J W van der Laan ，Reina E Mebius ，Jaap M J den Toonder ，Charlotte M de Winde
免疫/内分泌
淋巴瘤
细胞生物学
基质细胞
B细胞
发表日期：2025
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Integration of lymphatic vasculature to a human lymph node-on-chip enhances physiological immune properties

将淋巴管系统整合到芯片上的人类淋巴结中可增强其生理免疫特性。

期刊:Materials Today Bio
影响因子:8.7
doi:10.1016/j.mtbio.2025.102326
Andrew I Morrison ，Jonas Jäger ，Charlotte M de Winde ，Tanja Konijn ，Henk P Roest ，Luc J W van der Laan ，Susan Gibbs ，Jasper J Koning ，Reina E Mebius
免疫/内分泌
Human
发表日期：2025
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