日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Phase 2 study of ibrutinib in classic and variant hairy cell leukemia

伊布替尼治疗经典型和变异型毛细胞白血病的 II 期研究

Rogers, Kerry A; Andritsos, Leslie A; Wei, Lai; McLaughlin, Eric M; Ruppert, Amy S; Anghelina, Mirela; Blachly, James S; Call, Timothy; Chihara, Dai; Dauki, Anees; Guo, Ling; Ivy, S Percy; James, Lacey R; Jones, Daniel; Kreitman, Robert J; Lozanski, Gerard; Lucas, David M; Ngankeu, Apollinaire; Phelps, Mitch; Ravandi, Farhad; Schiffer, Charles A; Carson, William E; Jones, Jeffrey A; Grever, Michael R

The interleukin-3 receptor CD123 targeted SL-401 mediates potent cytotoxic activity against CD34(+)CD123(+) cells from acute myeloid leukemia/myelodysplastic syndrome patients and healthy donors

靶向白细胞介素-3受体CD123的SL-401对急性髓系白血病/骨髓增生异常综合征患者和健康供体的CD34(+)CD123(+)细胞具有强效的细胞毒活性。

Mani, Rajeswaran; Goswami, Swagata; Gopalakrishnan, Bhavani; Ramaswamy, Rahul; Wasmuth, Ronni; Tran, Minh; Mo, Xiaokui; Gordon, Amber; Bucci, Donna; Lucas, David M; Mims, Alice; Brooks, Christopher; Dorrance, Adrienne; Walker, Alison; Blum, William; Byrd, John C; Lozanski, Gerard; Vasu, Sumithira; Muthusamy, Natarajan

PTPROt inactivates the oncogenic fusion protein BCR/ABL and suppresses transformation of K562 cells

PTPROt 可使致癌融合蛋白 BCR/ABL 失活,并抑制 K562 细胞的转化。

Motiwala, Tasneem; Majumder, Sarmila; Ghoshal, Kalpana; Kutay, Huban; Datta, Jharna; Roy, Satavisha; Lucas, David M; Jacob, Samson T

Trametinib for the treatment of IGHV4-34, MAP2K1-mutant variant hairy cell leukemia

曲美替尼用于治疗IGHV4-34、MAP2K1突变型毛细胞白血病

Andritsos, Leslie A; Grieselhuber, Nicole R; Anghelina, Mirela; Rogers, Kerry A; Roychowdhury, Sameek; Reeser, Julie W; Timmers, Cynthia D; Freud, Aharon G; Blachly, James S; Lucas, David M; Lozanski, Gerard; Jones, Jeffrey A; Williams, Katie; Oakes, Christopher; Jones, Dan; Grever, Michael R

Prognostic and biologic significance of long non-coding RNA profiling in younger adults with cytogenetically normal acute myeloid leukemia

长链非编码RNA谱分析在细胞遗传学正常的年轻成人急性髓系白血病中的预后和生物学意义

Papaioannou, Dimitrios; Nicolet, Deedra; Volinia, Stefano; Mrózek, Krzysztof; Yan, Pearlly; Bundschuh, Ralf; Carroll, Andrew J; Kohlschmidt, Jessica; Blum, William; Powell, Bayard L; Uy, Geoffrey L; Kolitz, Jonathan E; Wang, Eunice S; Eisfeld, Ann-Kathrin; Orwick, Shelley J; Lucas, David M; Caligiuri, Michael A; Stone, Richard M; Byrd, John C; Garzon, Ramiro; Bloomfield, Clara D

Daunorubicin-Loaded DNA Origami Nanostructures Circumvent Drug-Resistance Mechanisms in a Leukemia Model

载有柔红霉素的DNA折纸纳米结构可克服白血病模型中的耐药机制

Halley, Patrick D; Lucas, Christopher R; McWilliams, Emily M; Webber, Matthew J; Patton, Randy A; Kural, Comert; Lucas, David M; Byrd, John C; Castro, Carlos E

Persistence of DNMT3A R882 mutations during remission does not adversely affect outcomes of patients with acute myeloid leukaemia

缓解期DNMT3A R882突变的持续存在不会对急性髓系白血病患者的预后产生不利影响。

Bhatnagar, Bhavana; Eisfeld, Ann-Kathrin; Nicolet, Deedra; Mrózek, Krzysztof; Blachly, James S; Orwick, Shelley; Lucas, David M; Kohlschmidt, Jessica; Blum, William; Kolitz, Jonathan E; Stone, Richard M; Bloomfield, Clara D; Byrd, John C

Discovery of Anticancer Agents of Diverse Natural Origin

发现多种天然来源的抗癌剂

Kinghorn, A Douglas; DE Blanco, Esperanza J Carcache; Lucas, David M; Rakotondraibe, H Liva; Orjala, Jimmy; Soejarto, D Doel; Oberlies, Nicholas H; Pearce, Cedric J; Wani, Mansukh C; Stockwell, Brent R; Burdette, Joanna E; Swanson, Steven M; Fuchs, James R; Phelps, Mitchell A; Xu, Lihui; Zhang, Xiaoli; Shen, Young Yongchun

Reduced dose pentostatin for initial management of hairy cell leukemia patients who have active infection or risk of hemorrhage is safe and effective

对于伴有活动性感染或出血风险的毛细胞白血病患者,初始治疗采用低剂量喷司他丁是安全有效的。

Andritsos, Leslie A; Dunavin, Neil; Lozanski, Gerard; Jones, Jeffrey A; Blachly, James S; Lucas, David M; Byrd, John C; Kraut, Eric; Grever, Michael R

Sorbicillinoid analogs with cytotoxic and selective anti-Aspergillus activities from Scytalidium album

从白花镰孢菌(Scytalidium album)中分离得到的具有细胞毒性和选择性抗曲霉活性的山梨醇类化合物。

El-Elimat, Tamam; Raja, Huzefa A; Figueroa, Mario; Swanson, Steven M; Falkinham, Joseph O 3rd; Lucas, David M; Grever, Michael R; Wani, Mansukh C; Pearce, Cedric J; Oberlies, Nicholas H