Lucas Trevor相关文献与解析，生知库 | 链接生命科学的每一步

Koenighofer, Martin; Parzefall, Thomas; Frohne, Alexandra; Frei, Elisabeth; Schoefer, Christian; Laccone, Franco; Feil, Patricia; Frei, Klemens; Lucas, Trevor

发表日期：2021

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A Novel Variant in the TBC1D24 Lipid-Binding Pocket Causes Autosomal Dominant Hearing Loss: Evidence for a Genotype-Phenotype Correlation

TBC1D24脂质结合口袋中的一种新型变异导致常染色体显性遗传性听力损失：基因型-表型相关性的证据

期刊:Frontiers in Cellular Neuroscience

影响因子:4

doi:10.3389/fncel.2020.585669

Parzefall, Thomas; Frohne, Alexandra; Koenighofer, Martin; Neesen, Juergen; Laccone, Franco; Eckl-Dorna, Julia; Waters, Jonathan J; Schreiner, Markus; Amr, Sami Samir; Ashton, Emma; Schoefer, Christian; Gstœttner, Wolfgang; Frei, Klemens; Lucas, Trevor

发表日期：2020

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Identification of a rare COCH mutation by whole-exome sequencing : Implications for personalized therapeutic rehabilitation in an Austrian family with non-syndromic autosomal dominant late-onset hearing loss

通过全外显子组测序鉴定出一种罕见的COCH基因突变：对奥地利一个患有非综合征型常染色体显性遗传性晚发性听力损失的家庭进行个性化治疗康复的意义

期刊:Wiener Klinische Wochenschrift

影响因子:2.1

doi:10.1007/s00508-017-1230-y

Parzefall, Thomas; Frohne, Alexandra; Koenighofer, Martin; Kirchnawy, Andreas; Streubel, Berthold; Schoefer, Christian; Gstoettner, Wolfgang; Frei, Klemens; Lucas, Trevor

发表日期：2018

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Whole-exome sequencing to identify the cause of congenital sensorineural hearing loss in carriers of a heterozygous GJB2 mutation

对携带杂合GJB2突变的患者进行全外显子组测序，以确定先天性感觉神经性听力损失的病因

期刊:European Archives of Oto-Rhino-Laryngology

影响因子:2.2

doi:10.1007/s00405-017-4699-0

Parzefall, Thomas; Frohne, Alexandra; Koenighofer, Martin; Kirchnawy, Andreas; Streubel, Berthold; Schoefer, Christian; Frei, Klemens; Lucas, Trevor

发表日期：2017

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Targeting Cdc42 with the small molecule drug AZA197 suppresses primary colon cancer growth and prolongs survival in a preclinical mouse xenograft model by downregulation of PAK1 activity

利用小分子药物AZA197靶向Cdc42，可通过下调PAK1活性，抑制原发性结肠癌的生长，并在临床前小鼠异种移植模型中延长生存期。

期刊:Journal of Translational Medicine

影响因子:7.5

doi:10.1186/1479-5876-11-295

Zins, Karin; Gunawardhana, Sandun; Lucas, Trevor; Abraham, Dietmar; Aharinejad, Seyedhossein

Inhibition of stromal PlGF suppresses the growth of prostate cancer xenografts

抑制基质PlGF可抑制前列腺癌异种移植瘤的生长

期刊:International Journal of Molecular Sciences

影响因子:4.9

doi:10.3390/ijms140917958

Zins, Karin; Thomas, Anita; Lucas, Trevor; Sioud, Mouldy; Aharinejad, Seyedhossein; Abraham, Dietmar

A Rac1/Cdc42 GTPase-specific small molecule inhibitor suppresses growth of primary human prostate cancer xenografts and prolongs survival in mice.

Rac1/Cdc42 GTPase 特异性小分子抑制剂可抑制原发性人类前列腺癌异种移植瘤的生长，并延长小鼠的生存期

期刊:PLoS One

影响因子:2.6

doi:10.1371/journal.pone.0074924

Zins Karin, Lucas Trevor, Reichl Patrick, Abraham Dietmar, Aharinejad Seyedhossein

Stromal cell-derived CSF-1 blockade prolongs xenograft survival of CSF-1-negative neuroblastoma

基质细胞来源的 CSF-1 阻断可延长 CSF-1 阴性神经母细胞瘤异种移植的存活时间

期刊:International Journal of Cancer

影响因子:4.7

doi:10.1002/ijc.24859

Abraham, Dietmar; Zins, Karin; Sioud, Mouldy; Lucas, Trevor; Schäfer, Romana; Stanley, E Richard; Aharinejad, Seyedhossein

Adenoviral-mediated endothelial precursor cell delivery of soluble CD115 suppresses human prostate cancer xenograft growth in mice.

腺病毒介导的内皮前体细胞递送可溶性 CD115 可抑制小鼠体内人前列腺癌异种移植瘤的生长

期刊:Stem Cells

影响因子:3.6

doi:10.1002/stem.145

Lucas Trevor, Abraham Dietmar, Untergasser Gerold, Zins Karin, Hofer Erhard, Gunsilius Eberhard, Aharinejad Seyedhossein

Incomplete penetrance of a novel SDHD variation causing familial head and neck paraganglioma

一种新型SDHD变异导致家族性头颈部副神经节瘤，其外显率不完全。

A Novel Variant in the TBC1D24 Lipid-Binding Pocket Causes Autosomal Dominant Hearing Loss: Evidence for a Genotype-Phenotype Correlation

TBC1D24脂质结合口袋中的一种新型变异导致常染色体显性遗传性听力损失：基因型-表型相关性的证据

Identification of a rare COCH mutation by whole-exome sequencing : Implications for personalized therapeutic rehabilitation in an Austrian family with non-syndromic autosomal dominant late-onset hearing loss

通过全外显子组测序鉴定出一种罕见的COCH基因突变：对奥地利一个患有非综合征型常染色体显性遗传性晚发性听力损失的家庭进行个性化治疗康复的意义

Whole-exome sequencing to identify the cause of congenital sensorineural hearing loss in carriers of a heterozygous GJB2 mutation

对携带杂合GJB2突变的患者进行全外显子组测序，以确定先天性感觉神经性听力损失的病因

Targeting Cdc42 with the small molecule drug AZA197 suppresses primary colon cancer growth and prolongs survival in a preclinical mouse xenograft model by downregulation of PAK1 activity

利用小分子药物AZA197靶向Cdc42，可通过下调PAK1活性，抑制原发性结肠癌的生长，并在临床前小鼠异种移植模型中延长生存期。

Inhibition of stromal PlGF suppresses the growth of prostate cancer xenografts

抑制基质PlGF可抑制前列腺癌异种移植瘤的生长

A Rac1/Cdc42 GTPase-specific small molecule inhibitor suppresses growth of primary human prostate cancer xenografts and prolongs survival in mice.

Rac1/Cdc42 GTPase 特异性小分子抑制剂可抑制原发性人类前列腺癌异种移植瘤的生长，并延长小鼠的生存期

Stromal cell-derived CSF-1 blockade prolongs xenograft survival of CSF-1-negative neuroblastoma

基质细胞来源的 CSF-1 阻断可延长 CSF-1 阴性神经母细胞瘤异种移植的存活时间

Adenoviral-mediated endothelial precursor cell delivery of soluble CD115 suppresses human prostate cancer xenograft growth in mice.

腺病毒介导的内皮前体细胞递送可溶性 CD115 可抑制小鼠体内人前列腺癌异种移植瘤的生长