日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Clozapine suppresses NADPH oxidase activation, counteracts cytosolic H2O2, and triggers early onset mitochondrial dysfunction during adipogenesis of human liposarcoma SW872 cells

氯氮平抑制 NADPH 氧化酶活化,拮抗胞质 H2O2,并在人脂肪肉瘤 SW872 细胞的脂肪生成过程中诱发早期线粒体功能障碍。

Giulia Blandino,Mara Fiorani,Barbara Canonico,Rita De Matteis,Andrea Guidarelli,Mariele Montanari,Gloria Buffi,Lucia Coppo,Elias S J Arnér,Orazio Cantoni

Mitochondrial depletion of glutaredoxin 2 induces metabolic dysfunction-associated fatty liver disease in mice

谷胱甘肽2的线粒体耗竭会诱发小鼠代谢功能障碍相关的脂肪肝疾病

Valeria Scalcon, Alessandra Folda, Maria Giovanna Lupo, Federica Tonolo, Naixuan Pei, Ilaria Battisti, Nicola Ferri, Giorgio Arrigoni, Alberto Bindoli, Arne Holmgren, Lucia Coppo, Maria Pia Rigobello

Supplemental Ascorbate Diminishes DNA Damage Yet Depletes Glutathione and Increases Acute Liver Failure in a Mouse Model of Hepatic Antioxidant System Disruption

在肝脏抗氧化系统紊乱的小鼠模型中,补充抗坏血酸可减少 DNA 损伤,但会消耗谷胱甘肽并增加急性肝衰竭

Colin G Miller, Jean A Kundert, Justin R Prigge, Julie A Amato, Allison E Perez, Lucia Coppo, Gabrielle N Rizzo, Michael P Kavanaugh, David J Orlicky, Colin T Shearn, Edward E Schmidt

Glutathione Fine-Tunes the Innate Immune Response toward Antiviral Pathways in a Macrophage Cell Line Independently of Its Antioxidant Properties

谷胱甘肽独立于其抗氧化特性,微调巨噬细胞系对抗病毒途径的先天免疫反应

Marina Diotallevi, Paola Checconi, Anna Teresa Palamara, Ignacio Celestino, Lucia Coppo, Arne Holmgren, Kahina Abbas, Fabienne Peyrot, Manuela Mengozzi, Pietro Ghezzi

Nitric Oxide Protects against Infection-Induced Neuroinflammation by Preserving the Stability of the Blood-Brain Barrier

一氧化氮通过维持血脑屏障的稳定性来预防感染引起的神经炎症

Gabriela C Olivera, Xiaoyuan Ren, Suman K Vodnala, Jun Lu, Lucia Coppo, Chaniya Leepiyasakulchai, Arne Holmgren, Krister Kristensson, Martin E Rottenberg

Linkage of inflammation and oxidative stress via release of glutathionylated peroxiredoxin-2, which acts as a danger signal

通过释放谷胱甘肽过氧化物酶-2(一种危险信号)连接炎症和氧化应激

Sonia Salzano, Paola Checconi, Eva-Maria Hanschmann, Christopher Horst Lillig, Lucas D Bowler, Philippe Chan, David Vaudry, Manuela Mengozzi, Lucia Coppo, Sandra Sacre, Kondala R Atkuri, Bita Sahaf, Leonard A Herzenberg, Leonore A Herzenberg, Lisa Mullen, Pietro Ghezzi