日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Staggered immunization with mRNA vaccines encoding SARS-CoV-2 polymerase or spike antigens broadens the T cell epitope repertoire

使用编码 SARS-CoV-2 聚合酶或刺突抗原的 mRNA 疫苗进行交错免疫可拓宽 T 细胞表位库

Evan R Abt #, Alex K Lam #, Miyako Noguchi, Khalid Rashid, Jami McLaughlin, Pu-Lin Teng, Wendy Tran, Donghui Cheng, Pavlo A Nesterenko, Zhiyuan Mao, Amanda L Creech, Giselle Burton Sojo, Arjit Vijey Jeyachandran, Ying K Tam, Jill E Henley, Lucio Comai, Norbert Pardi, Vaithilingaraja Arumugaswami, Ow

Potent NKT cell ligands overcome SARS-CoV-2 immune evasion to mitigate viral pathogenesis in mouse models

强效 NKT 细胞配体可克服 SARS-CoV-2 免疫逃避,从而减轻小鼠模型中的病毒致病机制

Hongjia Lu, Zhewei Liu, Xiangxue Deng, Siyang Chen, Ruiting Zhou, Rongqi Zhao, Ramya Parandaman, Amarjot Thind, Jill Henley, Lei Tian, Jianhua Yu, Lucio Comai, Pinghui Feng, Weiming Yuan

Mbnl2 loss alters novel context processing and impairs object recognition memory

Mbnl2 缺失会改变新情境处理并损害物体识别记忆

Abinash Khandelwal, Jesse Cushman, Jongkyu Choi, Irina Zhuravka, Abha Rajbhandari, Parvin Valiulahi, Xiandu Li, Chenyu Zhou, Lucio Comai, Sita Reddy

Differential Outcomes of Infection by Wild-Type SARS-CoV-2 and the B.1.617.2 and B.1.1.529 Variants of Concern in K18-hACE2 Transgenic Mice

K18-hACE2 转基因小鼠感染野生型 SARS-CoV-2 和值得关注的 B.1.617.2 和 B.1.1.529 变体的差异结果

Yicheng He, Jill Henley, Philip Sell, Lucio Comai

A GABA-receptor agonist reduces pneumonitis severity, viral load, and death rate in SARS-CoV-2-infected mice

GABA受体激动剂可降低SARS-CoV-2感染小鼠的肺炎严重程度、病毒载量和死亡率。

Jide Tian ,Barbara J Dillion ,Jill Henley ,Lucio Comai ,Daniel L Kaufman

WRN modulates translation by influencing nuclear mRNA export in HeLa cancer cells

WRN 通过影响 HeLa 癌细胞中的核 mRNA 输出来调节翻译

Juan Manuel Iglesias-Pedraz, Diego Matia Fossatti-Jara, Valeria Valle-Riestra-Felice, Sergio Rafael Cruz-Visalaya, Jose Antonio Ayala Felix, Lucio Comai

Measurements of Hydrogen Peroxide and Oxidative DNA Damage in a Cell Model of Premature Aging

过早衰老细胞模型中过氧化氢和氧化性 DNA 损伤的测量

Juan Manuel Iglesias-Pedraz, Lucio Comai

The Werner Syndrome Helicase Coordinates Sequential Strand Displacement and FEN1-Mediated Flap Cleavage during Polymerase δ Elongation

沃纳综合征解旋酶在聚合酶δ延伸过程中协调顺序链置换和FEN1介导的瓣状结构切割

Baomin Li ,Sita Reddy ,Lucio Comai

Loss of muscleblind-like 1 results in cardiac pathology and persistence of embryonic splice isoforms

肌盲样 1 的缺失导致心脏病理学和胚胎剪接异构体的持续存在

Donald M Dixon, Jongkyu Choi, Ayea El-Ghazali, Sun Young Park, Kenneth P Roos, Maria C Jordan, Michael C Fishbein, Lucio Comai, Sita Reddy

Downregulation of the Werner syndrome protein induces a metabolic shift that compromises redox homeostasis and limits proliferation of cancer cells

沃纳综合征蛋白的下调会引发代谢转变,破坏氧化还原稳态并限制癌细胞的增殖

Baomin Li, Juan Manuel Iglesias-Pedraz, Leng-Ying Chen, Fei Yin, Enrique Cadenas, Sita Reddy, Lucio Comai