文献库，生知库 | 链接生命科学的每一步

Luck Cuyler, Luo Yongfeng, Vasileva Elena, Jacobs Kyle A, Riad Julia, Macaraig Christopher D, Ponce Rovingaile Kriska M, Amatruda James F, Okimoto Ross A

肿瘤

发表日期：2026

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The CIC::DUX4 oncoprotein maintains DNA integrity through direct regulation of the catalytic subunit of DNA polymerase epsilon (POLE).

CIC::DUX4 癌蛋白通过直接调节 DNA 聚合酶 ε (POLE) 的催化亚基来维持 DNA 的完整性。

期刊:Oncogene

影响因子:7.3

doi:10.1038/s41388-025-03507-9

Kosibaty Zeinab, Luck Cuyler, Okimoto Ross A

First Generation Tools for the Modeling of Capicua (CIC) - Family Fusion Oncoprotein-Driven Cancers.

第一代 Capicua (CIC) 家族融合癌蛋白驱动癌症建模工具

期刊:

影响因子:

doi:10.1101/2025.05.13.653825

Luck Cuyler, Jacobs Kyle A, Riad Julia, Macaraig Christopher D, Ponce Rovingaile Kriska M, Okimoto Ross A

Molecular and therapeutic advancements in Capicua (CIC)-rearranged sarcoma

Capicua (CIC) 重排肉瘤的分子和治疗进展

期刊:Frontiers in Cell and Developmental Biology

影响因子:4.3

doi:10.3389/fcell.2024.1416697

Ponce, Rovingaile Kriska M; Luck, Cuyler; Okimoto, Ross A

发表日期：2024

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Mapping chromatin state and transcriptional response in CIC-DUX4 undifferentiated round cell sarcoma

CIC-DUX4未分化圆形细胞肉瘤染色质状态和转录反应的定位

期刊:

影响因子:

doi:10.1101/2023.10.11.561932

Thomas, Nicholas J; Luck, Cuyler; Shlimon, Nicole; Ponce, Rovingaile Kriska; Kosibaty, Zeinab; Okimoto, Ross A

Modeling of Capicua Family Fusion Oncoprotein-Driven Cancers Reveals Gene-Specific Functionality.

Capicua家族融合癌蛋白驱动的癌症建模揭示了基因特异性功能。

The CIC::DUX4 oncoprotein maintains DNA integrity through direct regulation of the catalytic subunit of DNA polymerase epsilon (POLE).

CIC::DUX4 癌蛋白通过直接调节 DNA 聚合酶 ε (POLE) 的催化亚基来维持 DNA 的完整性。

First Generation Tools for the Modeling of Capicua (CIC) - Family Fusion Oncoprotein-Driven Cancers.

第一代 Capicua (CIC) 家族融合癌蛋白驱动癌症建模工具

Molecular and therapeutic advancements in Capicua (CIC)-rearranged sarcoma

Capicua (CIC) 重排肉瘤的分子和治疗进展

Mapping chromatin state and transcriptional response in CIC-DUX4 undifferentiated round cell sarcoma

CIC-DUX4未分化圆形细胞肉瘤染色质状态和转录反应的定位