Lucy R Wedderburn相关文献与解析，生知库

Hannah Peckham ,Anna Radziszewska ,Justyna Sikora ,Nina M de Gruijter ,Restuadi Restuadi ,Melissa Kartawinata ,Lucia Martin-Gutierrez ,George A Robinson ,Claire T Deakin ,Lucy R Wedderburn ,Elizabeth C Jury ,Gary Butler ,Emma S Chambers ,Elizabeth C Rosser # ,Coziana Ciurtin #

B细胞

细胞生物学

免疫/内分泌

发表日期：2025

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Type I interferon and mitochondrial dysfunction are associated with dysregulated cytotoxic CD8+ T cell responses in juvenile systemic lupus erythematosus

I型干扰素和线粒体功能障碍与幼年系统性红斑狼疮中细胞毒性CD8+ T细胞反应失调有关

期刊:Clinical and Experimental Immunology

影响因子:3.4

doi:10.1093/cei/uxae127

Anna Radziszewska ，Hannah Peckham ，Restuadi Restuadi ，Melissa Kartawinata ，Dale Moulding ，Nina M de Gruijter ，George A Robinson ，Maryam Butt ，Claire T Deakin ，Meredyth G Ll Wilkinson ，Lucy R Wedderburn ，Elizabeth C Jury ，Elizabeth C Rosser ，Coziana Ciurtin

Favorable antibody responses to human coronaviruses in children and adolescents with autoimmune rheumatic diseases

患有自身免疫性风湿病的儿童和青少年对人类冠状病毒的有利抗体反应

期刊:Med

影响因子:12.8

doi:10.1016/j.medj.2021.08.001

Claire T Deakin ，Georgina H Cornish ，Kevin W Ng ，Nikhil Faulkner ，William Bolland ，Joshua Hope ，Annachiara Rosa ，Ruth Harvey ，Saira Hussain ，Christopher Earl ，Bethany R Jebson ，Meredyth G L L Wilkinson ，Lucy R Marshall ，Kathryn O'Brien ，Elizabeth C Rosser ，Anna Radziszewska ，Hannah Peckham ，Harsita Patel ，Judith Heaney ，Hannah Rickman ，Stavroula Paraskevopoulou ，Catherine F Houlihan ，Moira J Spyer ，Steve J Gamblin ，John McCauley ，Eleni Nastouli ，Michael Levin ，Peter Cherepanov ，Coziana Ciurtin ，Lucy R Wedderburn ，George Kassiotis

Microbiota-Derived Metabolites Suppress Arthritis by Amplifying Aryl-Hydrocarbon Receptor Activation in Regulatory B Cells

微生物群衍生的代谢物通过增强调节性B细胞中芳烃受体的激活来抑制关节炎

期刊:Cell Metabolism

影响因子:27.7

doi:10.1016/j.cmet.2020.03.003

Elizabeth C Rosser ，Christopher J M Piper ，Diana E Matei ，Paul A Blair ，André F Rendeiro ，Michael Orford ，Dagmar G Alber ，Thomas Krausgruber ，Diego Catalan ，Nigel Klein ，Jessica J Manson ，Ignat Drozdov ，Christoph Bock ，Lucy R Wedderburn ，Simon Eaton ，Claudia Mauri

Diapedesis-Induced Integrin Signaling via LFA-1 Facilitates Tissue Immunity by Inducing Intrinsic Complement C3 Expression in Immune Cells

白细胞渗出诱导的整合素信号通过LFA-1介导，诱导免疫细胞内源性补体C3表达，从而促进组织免疫。

期刊:Immunity

影响因子:25.5

doi:10.1016/j.immuni.2020.02.006

Martin Kolev ，Erin E West ，Natalia Kunz ，Daniel Chauss ，E Ashley Moseman ，Jubayer Rahman ，Tilo Freiwald ，Maria L Balmer ，Jonas Lötscher ，Sarah Dimeloe ，Elizabeth C Rosser ，Lucy R Wedderburn ，Katrin D Mayer-Barber ，Andrea Bohrer ，Paul Lavender ，Andrew Cope ，Luopin Wang ，Mariana J Kaplan ，Niki M Moutsopoulos ，Dorian McGavern ，Steven M Holland ，Christoph Hess ，Majid Kazemian ，Behdad Afzali ，Claudia Kemper

Sex and Pubertal Differences in the Type 1 Interferon Pathway Associate With Both X Chromosome Number and Serum Sex Hormone Concentration

I型干扰素通路中的性别和青春期差异与X染色体数目和血清性激素浓度均相关

期刊:Frontiers in Immunology

影响因子:5.7

doi:10.3389/fimmu.2018.03167

Kate Webb ，Hannah Peckham ，Anna Radziszewska ，Madhvi Menon ，Paola Oliveri ，Fraser Simpson ，Claire T Deakin ，Sophie Lee ，Coziana Ciurtin ，Gary Butler ，Lucy R Wedderburn ，Yiannis Ioannou

The transcription factor CREM drives an inflammatory phenotype of T cells in oligoarticular juvenile idiopathic arthritis

转录因子 CREM 驱动少关节型幼年特发性关节炎中 T 细胞的炎症表型

期刊:Pediatric Rheumatology

影响因子:

doi:10.1186/s12969-018-0253-x

Kim Ohl, Helge Nickel, Halima Moncrieffe, Patricia Klemm, Anja Scheufen, Dirk Föll, Viktor Wixler, Angela Schippers, Norbert Wagner, Lucy R Wedderburn, Klaus Tenbrock

CD161+ Tconv and CD161+ Treg Share a Transcriptional and Functional Phenotype despite Limited Overlap in TCRβ Repertoire

CD161+ Tconv 和 CD161+ Treg 尽管 TCRβ 库重叠有限，但仍具有共同的转录和功能表型

期刊:Frontiers in Immunology

影响因子:5.7

doi:10.3389/fimmu.2017.00103

Chantal L Duurland, Chrysothemis C Brown, Ryan F L O'Shaughnessy, Lucy R Wedderburn

Correlation of low CD73 expression on synovial lymphocytes with reduced adenosine generation and higher disease severity in juvenile idiopathic arthritis

滑膜淋巴细胞 CD73 表达水平低与幼年特发性关节炎腺苷生成减少及病情严重程度增加的相关性

期刊:Arthritis & Rheumatology

影响因子:11.4

doi:10.1002/art.38959

Sophie Botta Gordon-Smith, Simona Ursu, Simon Eaton, Halima Moncrieffe, Lucy R Wedderburn

Synovial Regulatory T Cells Occupy a Discrete TCR Niche in Human Arthritis and Require Local Signals To Stabilize FOXP3 Protein Expression

滑膜调节性 T 细胞在人类关节炎中占据离散的 TCR 微环境，需要局部信号来稳定 FOXP3 蛋白表达

期刊:Journal of Immunology

影响因子:3.6

doi:10.4049/jimmunol.1500391

David Bending, Eirini Giannakopoulou, Hannah Lom, Lucy R Wedderburn

Estrogen influences class-switched memory B cell frequency only in humans with two X chromosomes

雌激素仅影响拥有两条X染色体的人类中类别转换记忆B细胞的频率。

Type I interferon and mitochondrial dysfunction are associated with dysregulated cytotoxic CD8+ T cell responses in juvenile systemic lupus erythematosus

I型干扰素和线粒体功能障碍与幼年系统性红斑狼疮中细胞毒性CD8+ T细胞反应失调有关

Favorable antibody responses to human coronaviruses in children and adolescents with autoimmune rheumatic diseases

患有自身免疫性风湿病的儿童和青少年对人类冠状病毒的有利抗体反应

Microbiota-Derived Metabolites Suppress Arthritis by Amplifying Aryl-Hydrocarbon Receptor Activation in Regulatory B Cells

微生物群衍生的代谢物通过增强调节性B细胞中芳烃受体的激活来抑制关节炎

Diapedesis-Induced Integrin Signaling via LFA-1 Facilitates Tissue Immunity by Inducing Intrinsic Complement C3 Expression in Immune Cells

白细胞渗出诱导的整合素信号通过LFA-1介导，诱导免疫细胞内源性补体C3表达，从而促进组织免疫。

Sex and Pubertal Differences in the Type 1 Interferon Pathway Associate With Both X Chromosome Number and Serum Sex Hormone Concentration

I型干扰素通路中的性别和青春期差异与X染色体数目和血清性激素浓度均相关

The transcription factor CREM drives an inflammatory phenotype of T cells in oligoarticular juvenile idiopathic arthritis

转录因子 CREM 驱动少关节型幼年特发性关节炎中 T 细胞的炎症表型

CD161+ Tconv and CD161+ Treg Share a Transcriptional and Functional Phenotype despite Limited Overlap in TCRβ Repertoire

CD161+ Tconv 和 CD161+ Treg 尽管 TCRβ 库重叠有限，但仍具有共同的转录和功能表型

Correlation of low CD73 expression on synovial lymphocytes with reduced adenosine generation and higher disease severity in juvenile idiopathic arthritis

滑膜淋巴细胞 CD73 表达水平低与幼年特发性关节炎腺苷生成减少及病情严重程度增加的相关性

Synovial Regulatory T Cells Occupy a Discrete TCR Niche in Human Arthritis and Require Local Signals To Stabilize FOXP3 Protein Expression

滑膜调节性 T 细胞在人类关节炎中占据离散的 TCR 微环境，需要局部信号来稳定 FOXP3 蛋白表达