日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Covalent Degraders of Immune Regulatory Transcription Factors IRF8 and IRF5

免疫调节转录因子IRF8和IRF5的共价降解剂

Do, Thang Cong; Chan, Henry; Greene, Justin; Sabaat, Sam; Ludwig, Connor; Abell, Nathan S; Albert, Matthew L; Kosuri, Sriram; Nomura, Daniel K

A comprehensive map of missense trafficking variants in rhodopsin and their response to pharmacologic correction.

视紫红质错义转运变异及其对药物纠正的反应的综合图谱

Manian Kannan V, Ludwig Connor H, Zhao Yan, Abell Nathan, Yang Xiaoping, Root David E, Albert Matthew L, Comander Jason

Development of compact transcriptional effectors using high-throughput measurements in diverse contexts.

利用高通量测量在不同环境下开发紧凑型转录效应因子

Tycko Josh, Van Mike V, Aradhana, DelRosso Nicole, Ye Hanrong, Yao David, Valbuena Raeline, Vaughan-Jackson Alun, Xu Xiaoshu, Ludwig Connor, Spees Kaitlyn, Liu Katherine, Gu Mingxin, Khare Venya, Mukund Adi Xiyal, Suzuki Peter H, Arana Sophia, Zhang Catherine, Du Peter P, Ornstein Thea S, Hess Gaelen T, Kamber Roarke A, Qi Lei S, Khalil Ahmad S, Bintu Lacramioara, Bassik Michael C

The H3.3K36M oncohistone disrupts the establishment of epigenetic memory through loss of DNA methylation.

H3.3K36M 癌组蛋白通过 DNA 甲基化的丧失破坏表观遗传记忆的建立

Sinha Joydeb, Nickels Jan F, Thurm Abby R, Ludwig Connor H, Archibald Bella N, Hinks Michaela M, Wan Jun, Fang Dong, Bintu Lacramioara

Mapping chromatin modifications at the single cell level

在单细胞水平上绘制染色质修饰图谱

Ludwig, Connor H; Bintu, Lacramioara

Differential effects of partial and complete loss of TREM2 on microglial injury response and tauopathy

TREM2部分缺失和完全缺失对小胶质细胞损伤反应和tau蛋白病变的不同影响

Sayed, Faten A; Telpoukhovskaia, Maria; Kodama, Lay; Li, Yaqiao; Zhou, Yungui; Le, David; Hauduc, Axel; Ludwig, Connor; Gao, Fuying; Clelland, Claire; Zhan, Lihong; Cooper, Yonatan A; Davalos, Dimitrios; Akassoglou, Katerina; Coppola, Giovanni; Gan, Li

Individuals with progranulin haploinsufficiency exhibit features of neuronal ceroid lipofuscinosis

患有前粒蛋白单倍体不足的个体表现出神经元蜡样脂褐质沉积症的特征。

Ward, Michael E; Chen, Robert; Huang, Hsin-Yi; Ludwig, Connor; Telpoukhovskaia, Maria; Taubes, Ali; Boudin, Helene; Minami, Sakura S; Reichert, Meredith; Albrecht, Philipp; Gelfand, Jeffrey M; Cruz-Herranz, Andres; Cordano, Christian; Alavi, Marcel V; Leslie, Shannon; Seeley, William W; Miller, Bruce L; Bigio, Eileen; Mesulam, Marek-Marsel; Bogyo, Matthew S; Mackenzie, Ian R; Staropoli, John F; Cotman, Susan L; Huang, Eric J; Gan, Li; Green, Ari J