日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Evidence that transient replication errors initiate nuclear genome mutations

证据表明,瞬时复制错误会引发核基因组突变

Lujan, Scott A; Zhou, Zhi-Xiong; Kunkel, Thomas A

High fidelity DNA ligation prevents single base insertions in the yeast genome

高保真DNA连接可防止酵母基因组中出现单碱基插入。

Williams, Jessica S; Lujan, Scott A; Arana, Mercedes E; Burkholder, Adam B; Tumbale, Percy P; Williams, R Scott; Kunkel, Thomas A

Instability throughout the Saccharomyces cerevisiae genome resulting from Pms1 endonuclease deficiency

Pms1核酸内切酶缺乏导致酿酒酵母基因组整体不稳定。

Lujan, Scott A; Garbacz, Marta A; Liberti, Sascha E; Burkholder, Adam B; Kunkel, Thomas A

How asymmetric DNA replication achieves symmetrical fidelity

不对称DNA复制如何实现对称保真度

Zhou, Zhi-Xiong; Lujan, Scott A; Burkholder, Adam B; St Charles, Jordan; Dahl, Joseph; Farrell, Corinne E; Williams, Jessica S; Kunkel, Thomas A

Ribonucleotide incorporation into DNA during DNA replication and its consequences

DNA复制过程中核糖核苷酸掺入DNA及其后果

Zhou, Zhi-Xiong; Williams, Jessica S; Lujan, Scott A; Kunkel, Thomas A

Ultrasensitive deletion detection links mitochondrial DNA replication, disease, and aging

超灵敏的缺失检测揭示了线粒体DNA复制、疾病和衰老之间的联系

Lujan, Scott A; Longley, Matthew J; Humble, Margaret H; Lavender, Christopher A; Burkholder, Adam; Blakely, Emma L; Alston, Charlotte L; Gorman, Grainne S; Turnbull, Doug M; McFarland, Robert; Taylor, Robert W; Kunkel, Thomas A; Copeland, William C

Opportunities for new studies of nuclear DNA replication enzymology in budding yeast

出芽酵母核DNA复制酶学新研究的机遇

Garbacz, Marta A; Lujan, Scott A; Kunkel, Thomas A

The absence of the catalytic domains of Saccharomyces cerevisiae DNA polymerase ϵ strongly reduces DNA replication fidelity.

酿酒酵母 DNA 聚合酶 ϵ 催化结构域的缺失会严重降低 DNA 复制的保真度

Garbacz Marta A, Cox Phillip B, Sharma Sushma, Lujan Scott A, Chabes Andrei, Kunkel Thomas A

Genome-wide mutagenesis resulting from topoisomerase 1-processing of unrepaired ribonucleotides in DNA

拓扑异构酶I对DNA中未修复的核糖核苷酸进行加工,导致全基因组突变。

Williams, Jessica S; Lujan, Scott A; Zhou, Zhi-Xiong; Burkholder, Adam B; Clark, Alan B; Fargo, David C; Kunkel, Thomas A

Evidence that DNA polymerase δ contributes to initiating leading strand DNA replication in Saccharomyces cerevisiae.

证据表明,DNA聚合酶δ有助于启动酿酒酵母中的前导链DNA复制

Garbacz Marta A, Lujan Scott A, Burkholder Adam B, Cox Phillip B, Wu Qiuqin, Zhou Zhi-Xiong, Haber James E, Kunkel Thomas A