日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Dapiglutide, a dual GLP-1 and GLP-2 receptor agonist, for obesity: a randomised, double-blind, placebo-controlled parallel-group, proof-of-concept trial

达匹鲁肽(一种双重 GLP-1 和 GLP-2 受体激动剂)治疗肥胖症:一项随机、双盲、安慰剂对照、平行组的概念验证试验

Nielsen, Casper K; Pálsson, Thorir G; Forman, Julie L; Lukacova, Michaela; Jensen, Benjamin A H; Mathiesen, David S; Englund, Anders; Gether, Ida M; Johansen, Nicklas J; Pedersen, Miriam G; Hartmann, Bolette; Holst, Jens J; Knop, Filip K; Lund, Asger B

Prediction of Monoclonal Antibody Pharmacokinetics in Pediatric Populations Using PBPK Modeling and Simulation

利用PBPK建模和模拟预测单克隆抗体在儿科人群中的药代动力学

Zunino, Chiara; Gualano, Virginie; Zhou, Haiying; Lukacova, Viera; Le Merdy, Maxime

Physiologically Based Pharmacokinetic Models for Infliximab, Ipilimumab, and Nivolumab Developed with GastroPlus to Predict Hepatic Concentrations

利用 GastroPlus 开发基于生理的英夫利昔单抗、伊匹木单抗和纳武利尤单抗药代动力学模型,以预测肝脏浓度

Vallejo, Celeste; Meaney, Cameron; Clemens, Lara; Yang, Kyunghee; Lukacova, Viera; Zhou, Haiying

Leveraging Omeprazole PBPK/PD Modeling to Inform Drug-Drug Interactions and Specific Recommendations for Pediatric Labeling

利用奥美拉唑 PBPK/PD 模型指导药物相互作用研究,并为儿科用药标签提供具体建议

Soliman, Amira; Rodriguez-Vera, Leyanis; Alarcia-Lacalle, Ana; Pippa, Leandro F; Subhani, Saima; Lukacova, Viera; Duconge, Jorge; de Moraes, Natalia V; Vozmediano, Valvanera

PBPK Modeling to Support Bioavailability and Bioequivalence Assessment in Pediatric Populations

利用生理药代动力学模型支持儿科人群的生物利用度和生物等效性评估

Wu, Fang; Tsakalozou, Eleftheria; Burckart, Gilbert J; Žakelj, Rebeka; Gaohua, Lu; Sagawa, Kazuko; Lukacova, Viera; Vaithiyalingam, Siva; Fan, Jianghong; Fotaki, Nikoletta; Patel, Nikunjkumar; Fang, Lanyan

Mechanistic Modeling of Intramuscular Administration of a Long-acting Injectable Accounting for Tissue Response At the Depot Site

肌内注射长效注射剂的机制模型,考虑药物储存部位的组织反应

Silva, Daniela A; Le Merdy, Maxime; Mullin, James; Malavia, Nilesh; Alam, Khondoker; Tsakalozou, Eleftheria; Al Shoyaib, Abdullah; Wang, Yan; Burgess, Diane; Lukacova, Viera

Investigating the potential of diffusion tensor atlases to generate anisotropic clinical tumor volumes in glioblastoma patients

研究扩散张量图谱在胶质母细胞瘤患者中生成各向异性临床肿瘤体积的潜力

Hochreuter, Kim; Buti, Gregory; Ajdari, Ali; Bridge, Christopher P; Sharp, Gregory C; Jespersen, Sune; Lukacova, Slávka; Bortfeld, Thomas; Kallehauge, Jesper F

Exploring synergistic effects: Atorvastatin and electrical stimulation in spinal cord injury therapy.

探索协同效应:阿托伐他汀和电刺激在脊髓损伤治疗中的应用

Magurova Martina, Bacova Maria, Papcunova Stefania, Kiss Bimbova Katarina, Kuruc Tomas, Kisucka Alexandra, Ihnatova Lenka, Kucharova Karolina, Lukacova Nadezda, Galik Jan

Clinical evaluation of two glioblastoma delineation methods based on neural networks

基于神经网络的两种胶质母细胞瘤轮廓描绘方法的临床评价

Hansen, Anders Traberg; Askglæde, Johannes Thestrup; Kallehauge, Jesper Folsted; Vittrup, Anders Schwartz; Hochreuter, Kim; Lukacova, Slavka

Site of first treatment failure after standard-of-care for newly diagnosed glioblastoma in a Danish cohort

丹麦队列中新诊断的胶质母细胞瘤患者接受标准治疗后首次治疗失败的部位

Clarke, Alice Mary; Lukacova, Slavka; Hedegaard Dahlrot, Rikke; Aaquist Haslund, Charlotte; Muhic, Aida; Folsted Kallehauge, Jesper; Lind Laursen, Kasper; Rønn Hansen, Christian; Smulders, Bob; Trip, Anouk Kirsten