日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

An Imidazo[2,1-b][1,3,4]thiadiazole Derivative Inhibits the Virulence Factor α-Hemolysin by Blocking the Pullout of Its Stem Domain

一种咪唑并[2,1-b][1,3,4]噻二唑衍生物通过阻断α-溶血素茎区结构域的拉出来抑制该毒力因子。

Korotkov, Vadim S; Lukat, Peer; Di Lucrezia, Raffaella; Shekhar, Aditya; Degenhart, Carsten; Diestel, Randi; Bilitewski, Ursula; Dinkel, Klaus; Blankenfeldt, Wulf; Brönstrup, Mark

Deciphering the role of the distal pocket in Staphylococcus aureus coproheme decarboxylase

解析金黄色葡萄球菌粪血红素脱羧酶远端口袋的作用

Stiller, Olivia R; Streit, Bennett R; Honzay, Garrett; DuBois, Jennifer L; Rodgers, Kenton R; Lukat-Rodgers, Gudrun S

Elucidation of unusual biosynthesis and DnaN-targeting mode of action of potent anti-tuberculosis antibiotics Mycoplanecins

阐明强效抗结核抗生素 Mycoplanecins 的异常生物合成和 DnaN 靶向作用方式

Chengzhang Fu #, Yunkun Liu #, Christine Walt #, Sari Rasheed #, Chantal D Bader, Peer Lukat, Markus Neuber, F P Jake Haeckl, Wulf Blankenfeldt, Olga V Kalinina, Rolf Müller

Exquisite selectivity of griselimycin extends to beta subunit of DNA polymerases from Gram-negative bacterial pathogens

灰霉素对革兰氏阴性致病菌DNA聚合酶β亚基具有极高的选择性。

Fenwick, Michael K; Pierce, Phillip G; Abendroth, Jan; Barrett, Kayleigh F; Barrett, Lynn K; Bowatte, Kalinga; Choi, Ryan; Chun, Ian; Conrady, Deborah G; Craig, Justin K; Dranow, David M; Hammerson, Bradley; Higgins, Tate; Lorimer, Donald D; Lukat, Peer; Mayclin, Stephen J; Hewitt, Stephen Nakazawa; Peng, Ying Po; Shanbhogue, Ashwini; Smutney, Hayden; Stigliano, Matthew Z Z; Tillery, Logan M; Udell, Hannah S; Wallace, Ellen G; DeRocher, Amy E; Phan, Isabelle Q; Staker, Bart L; Subramanian, Sandhya; Van Voorhis, Wesley C; Blankenfeldt, Wulf; Müller, Rolf; Edwards, Thomas E; Myler, Peter J

Biochemical and structural elucidation of the L-carnitine degradation pathway of the human pathogen Acinetobacter baumannii

人类病原体鲍曼不动杆菌L-肉碱降解途径的生化和结构阐明

Fabian Piskol, Peer Lukat, Laurin Kaufhold, Alexander Heger, Wulf Blankenfeldt, Dieter Jahn, Jürgen Moser

NTRK Gene Fusions in Non-Small-Cell Lung Cancer: Real-World Screening Data of 1068 Unselected Patients

非小细胞肺癌中NTRK基因融合:1068例未经筛选患者的真实世界筛查数据

Overbeck, Tobias Raphael; Reiffert, Annika; Schmitz, Katja; Rittmeyer, Achim; Körber, Wolfgang; Hugo, Sara; Schnalke, Juliane; Lukat, Laura; Hugo, Tabea; Hinterthaner, Marc; Reuter-Jessen, Kirsten; Schildhaus, Hans-Ulrich

Molecular replacement for small-molecule crystal structure determination from X-ray and electron diffraction data with reduced resolution

利用分子置换法,从分辨率降低的X射线和电子衍射数据中确定小分子晶体结构。

Gorelik, Tatiana E; Lukat, Peer; Kleeberg, Christian; Blankenfeldt, Wulf; Mueller, Rolf

Roles of High-valent Hemes and pH Dependence in Halite Decomposition Catalyzed by Chlorite Dismutase from Dechloromonas aromatica

高价血红素和pH依赖性在脱氯单胞菌亚氯酸盐歧化酶催化的石盐分解中的作用

Geeraerts, Zachary; Stiller, Olivia R; Lukat-Rodgers, Gudrun S; Rodgers, Kenton R

Understanding and Engineering the Stereoselectivity of Humulene Synthase

理解和调控葎草烯合酶的立体选择性

Schotte, Carsten; Lukat, Peer; Deuschmann, Adrian; Blankenfeldt, Wulf; Cox, Russell J

Crystal structure of bacterial cytotoxic necrotizing factor CNFY reveals molecular building blocks for intoxication

细菌细胞毒性坏死因子 CNFY 的晶体结构揭示了中毒的分子构件

Paweena Chaoprasid, Peer Lukat, Sabrina Mühlen, Thomas Heidler, Emerich-Mihai Gazdag, Shuangshuang Dong, Wenjie Bi, Christian Rüter, Marco Kirchenwitz, Anika Steffen, Lothar Jänsch, Theresia E B Stradal, Petra Dersch, Wulf Blankenfeldt