日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Stathmin 1 regulates mitophagy and cellular function in hematopoietic stem cells

Stathmin 1 调节造血干细胞中的线粒体自噬和细胞功能

Chiquetto, Luana; Schuetz, Meg; Dong, Qian; Warmka, Mia; Valin, Liana; Jones, Ashley; Hunt, Patrick; Petermeier, Copper; Wang, Jie; Roundy, Nate; Greenberg, Zev J; Yang, Wei; Zhang, Christine R; Challen, Grant A; Luke, Cliff J; Signer, Robert A J; Beatty, Wandy L; Sykes, Stephen; Li, Weikai; Kast, David J; Schuettpelz, Laura G

A fluorescent reporter for rapid assessment of autophagic flux reveals unique autophagy signatures during C. elegans post-embryonic development and identifies compounds that modulate autophagy.

一种用于快速评估自噬通量的荧光报告分子揭示了秀丽隐杆线虫胚胎发育后独特的自噬特征,并鉴定了调节自噬的化合物

Dawson Zachary D, Sundaramoorthi Hemalatha, Regmi Suk, Zhang Bo, Morrison Stephanie, Fielder Sara M, Zhang Jessie R, Hoang Hieu, Perlmutter David H, Luke Cliff J, Silverman Gary A, Pak Stephen C

Preclinical mouse model of a misfolded PNLIP variant develops chronic pancreatitis

一种PNLIP变体错误折叠的临床前小鼠模型会发展为慢性胰腺炎

Zhu, Guoying; Wilhelm, Steven J; George, Leah G; Cassidy, Brett M; Zino, Sammy; Luke, Cliff J; Hanna, Mina; Stone, Stephen; Phan, Nhung; Matiwala, Neel; Ballentine, Samuel J; Lowe, Mark E; Xiao, Xunjun

The tetraspanin CD53 protects stressed hematopoietic stem cells via promotion of DREAM complex-mediated quiescence.

四跨膜蛋白 CD53 通过促进 DREAM 复合物介导的静止状态来保护受损的造血干细胞

Greenberg Zev J, Paracatu Luana Chiquetto, Monlish Darlene A, Dong Qian, Rettig Michael, Roundy Nate, Gaballa Rofaida, Li Weikai, Yang Wei, Luke Cliff J, Schuettpelz Laura G

Functional characterization of four ATP-binding cassette transporter A3 gene (ABCA3) variants

四种ATP结合盒转运蛋白A3基因(ABCA3)变体的功能表征

Hu, June Y; Yang, Ping; Wegner, Daniel J; Heins, Hillary B; Luke, Cliff J; Li, Fuhai; White, Frances V; Silverman, Gary A; Sessions Cole, F; Wambach, Jennifer A

Autophagy genes in myeloid cells counteract IFNγ-induced TNF-mediated cell death and fatal TNF-induced shock.

髓系细胞中的自噬基因可对抗 IFNγ 诱导的 TNF 介导的细胞死亡和致命的 TNF 诱导的休克

Orvedahl Anthony, McAllaster Michael R, Sansone Amy, Dunlap Bria F, Desai Chandni, Wang Ya-Ting, Balce Dale R, Luke Cliff J, Lee Sanghyun, Orchard Robert C, Artyomov Maxim N, Handley Scott A, Doench John G, Silverman Gary A, Virgin Herbert W

Breast Milk Enhances Growth of Enteroids: An Ex Vivo Model of Cell Proliferation

母乳促进肠类器官生长:细胞增殖的体外模型

Lanik, Wyatt E; Xu, Lily; Luke, Cliff J; Hu, Elise Z; Agrawal, Pranjal; Liu, Victoria S; Kumar, Rajesh; Bolock, Alexa M; Ma, Congrong; Good, Misty

Activation of the Caenorhabditis elegans Degenerin Channel by Shear Stress Requires the MEC-10 Subunit

剪切应力激活秀丽隐杆线虫退化蛋白通道需要MEC-10亚基

Shi, Shujie; Luke, Cliff J; Miedel, Mark T; Silverman, Gary A; Kleyman, Thomas R

The aggregation-prone intracellular serpin SRP-2 fails to transit the ER in Caenorhabditis elegans

线虫体内易聚集的细胞内丝氨酸蛋白酶抑制剂SRP-2无法通过内质网转运

Silverman, Richard M; Cummings, Erin E; O'Reilly, Linda P; Miedel, Mark T; Silverman, Gary A; Luke, Cliff J; Perlmutter, David H; Pak, Stephen C

Human SERPINB12 Is an Abundant Intracellular Serpin Expressed in Most Surface and Glandular Epithelia

人丝氨酸蛋白酶抑制剂B12(SERPINB12)是一种丰富的细胞内丝氨酸蛋白酶抑制剂,在大多数表面和腺上皮细胞中表达。

Niehaus, Jason Z; Good, Misty; Jackson, Laura E; Ozolek, John A; Silverman, Gary A; Luke, Cliff J