日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Transgenic expression of cif genes from Wolbachia strain wAlbB recapitulates cytoplasmic incompatibility in Aedes aegypti

沃尔巴克氏体菌株 wAlbB 的 cif 基因转基因表达重现了埃及伊蚊的细胞质不相容性

Cameron J McNamara, Thomas H Ant, Tim Harvey-Samuel, Helen White-Cooper, Julien Martinez, Luke Alphey, Steven P Sinkins

A multiplexed, confinable CRISPR/Cas9 gene drive can propagate in caged Aedes aegypti populations

多重、可控的 CRISPR/Cas9 基因驱动可以在笼养的埃及伊蚊种群中传播。

Michelle A E Anderson # ,Estela Gonzalez # ,Matthew P Edgington ,Joshua X D Ang ,Deepak-Kumar Purusothaman ,Lewis Shackleford ,Katherine Nevard ,Sebald A N Verkuijl ,Timothy Harvey-Samuel ,Philip T Leftwich ,Kevin Esvelt ,Luke Alphey

Closing the gap to effective gene drive in Aedes aegypti by exploiting germline regulatory elements

利用生殖系调控元件弥补埃及伊蚊有效基因驱动的差距

Michelle A E Anderson #, Estela Gonzalez #, Joshua X D Ang #, Lewis Shackleford, Katherine Nevard, Sebald A N Verkuijl, Matthew P Edgington, Tim Harvey-Samuel, Luke Alphey

Optimizing CRE and PhiC31 mediated recombination in Aedes aegypti

优化埃及伊蚊中 CRE 和 PhiC31 介导的重组

Leonela Z Carabajal Paladino, Ray Wilson, Priscilla Y L Tng, Vishaal Dhokiya, Elizabeth Keen, Piotr Cuber, Will Larner, Sara Rooney, Melanie Nicholls, Anastasia Uglow, Luke Williams, Michelle A E Anderson, Sanjay Basu, Philip T Leftwich, Luke Alphey

Expression of Alphavirus Nonstructural Protein 2 (nsP2) in Mosquito Cells Inhibits Viral RNA Replication in Both a Protease Activity-Dependent and -Independent Manner

蚊子细胞中 Alphavirus 非结构蛋白 2 (nsP2) 的表达以蛋白酶活性依赖性和非蛋白酶活性依赖性方式抑制病毒 RNA 复制

Liubov Cherkashchenko, Kai Rausalu, Sanjay Basu, Luke Alphey, Andres Merits

Combating mosquito-borne diseases using genetic control technologies

利用基因控制技术防治蚊媒疾病

Guan-Hong Wang #, Stephanie Gamez #, Robyn R Raban #, John M Marshall, Luke Alphey, Ming Li, Jason L Rasgon, Omar S Akbari

Quantifying and Modeling the Acquisition and Retention of Lumpy Skin Disease Virus by Hematophagus Insects Reveals Clinically but Not Subclinically Affected Cattle Are Promoters of Viral Transmission and Key Targets for Control of Disease Outbreaks

对吸血昆虫对结节性皮肤病病毒的获取和保留进行量化和建模,揭示了临床上受影响的牛是病毒传播的促进者,也是控制疾病爆发的关键目标

Beatriz Sanz-Bernardo, Ismar R Haga, Najith Wijesiriwardana, Sanjay Basu, Will Larner, Adriana V Diaz, Zoë Langlands, Eric Denison, Joanne Stoner, Mia White, Christopher Sanders, Philippa C Hawes, Anthony J Wilson, John Atkinson, Carrie Batten, Luke Alphey, Karin E Darpel, Simon Gubbins #, Philippa

nsP4 Is a Major Determinant of Alphavirus Replicase Activity and Template Selectivity

nsP4 是决定 Alphavirus 复制酶活性和模板选择性的主要因素

Laura Sandra Lello, Koen Bartholomeeusen, Sainan Wang, Sandra Coppens, Rennos Fragkoudis, Luke Alphey, Kevin K Ariën, Andres Merits, Age Utt

CRISPR/Cas-9 mediated knock-in by homology dependent repair in the West Nile Virus vector Culex quinquefasciatus Say

CRISPR/Cas-9 介导的西尼罗河病毒载体 Culex quinquefasciatus 中的同源性依赖性修复敲入

Deepak-Kumar Purusothaman #, Lewis Shackleford #, Michelle A E Anderson, Tim Harvey-Samuel, Luke Alphey

Cross-utilisation of template RNAs by alphavirus replicases

甲病毒复制酶对模板RNA的交叉利用

Laura Sandra Lello, Age Utt, Koen Bartholomeeusen, Sainan Wang, Kai Rausalu, Catherine Kendall, Sandra Coppens, Rennos Fragkoudis, Andrew Tuplin, Luke Alphey, Kevin K Ariën, Andres Merits