Luke Ames相关文献与解析，生知库 | 链接生命科学的每一步

Sophie G Kellaway ，Sandeep Potluri ，Peter Keane ，Helen J Blair ，Luke Ames ，Alice Worker ，Paulynn S Chin ，Anetta Ptasinska ，Polina K Derevyanko ，Assunta Adamo ，Daniel J L Coleman ，Naeem Khan ，Salam A Assi ，Anja Krippner-Heidenreich ，Manoj Raghavan ，Peter N Cockerill ，Olaf Heidenreich ，Constanze Bonifer

白血病

细胞生物学

信号转导

Pharmacological inhibition of RAS overcomes FLT3 inhibitor resistance in FLT3-ITD+ AML through AP-1 and RUNX1

RAS的药理学抑制可通过AP-1和RUNX1克服FLT3-ITD+ AML中的FLT3抑制剂耐药性

期刊:iScience

影响因子:4.6

doi:10.1016/j.isci.2024.109576

Daniel J L Coleman ，Peter Keane ，Paulynn S Chin ，Luke Ames ，Sophie Kellaway ，Helen Blair ，Naeem Khan ，James Griffin ，Elizabeth Holmes ，Alexander Maytum ，Sandeep Potluri ，Lara Strate ，Kinga Koscielniak ，Manoj Raghavan ，John Bushweller ，Olaf Heidenreich ，Terry Rabbitts ，Peter N Cockerill ，Constanze Bonifer

Identification and interrogation of the gene regulatory network of CEBPA-double mutant acute myeloid leukemia

CEBPA双突变急性髓系白血病基因调控网络的鉴定与探究

期刊:Leukemia

影响因子:12.8

doi:10.1038/s41375-022-01744-5

Assunta Adamo #, Paulynn Chin #, Peter Keane, Salam A Assi, Sandeep Potluri, Sophie G Kellaway, Daniel Coleman, Luke Ames, Anetta Ptasinska, H Ruud Delwel, Peter N Cockerill, Constanze Bonifer

Gene regulatory network analysis predicts cooperating transcription factor regulons required for FLT3-ITD+ AML growth

基因调控网络分析预测了FLT3-ITD+ AML生长所需的协同转录因子调控子。

期刊:Cell Reports

影响因子:7.5

doi:10.1016/j.celrep.2023.113568

Daniel J L Coleman,Peter Keane,Rosario Luque-Martin,Paulynn S Chin,Helen Blair,Luke Ames,Sophie G Kellaway,James Griffin,Elizabeth Holmes,Sandeep Potluri,Salam A Assi,John Bushweller,Olaf Heidenreich,Peter N Cockerill,Constanze Bonifer

RUNX1-ETO Depletion in t(8;21) AML Leads to C/EBPα- and AP-1-Mediated Alterations in Enhancer-Promoter Interaction

t(8;21) AML 中 RUNX1-ETO 的缺失导致 C/EBPα 和 AP-1 介导的增强子-启动子相互作用改变

期刊:Cell Reports

影响因子:7.5

doi:10.1016/j.celrep.2019.08.040

Anetta Ptasinska ,Anna Pickin ,Salam A Assi ,Paulynn Suyin Chin ,Luke Ames ,Roberto Avellino ,Stefan Gröschel ,Ruud Delwel ,Peter N Cockerill ,Cameron S Osborne ,Constanze Bonifer

Leukemic stem cells activate lineage inappropriate signalling pathways to promote their growth

白血病干细胞激活谱系异常信号通路以促进自身生长

Pharmacological inhibition of RAS overcomes FLT3 inhibitor resistance in FLT3-ITD+ AML through AP-1 and RUNX1

RAS的药理学抑制可通过AP-1和RUNX1克服FLT3-ITD+ AML中的FLT3抑制剂耐药性

Identification and interrogation of the gene regulatory network of CEBPA-double mutant acute myeloid leukemia

CEBPA双突变急性髓系白血病基因调控网络的鉴定与探究

Gene regulatory network analysis predicts cooperating transcription factor regulons required for FLT3-ITD+ AML growth

基因调控网络分析预测了FLT3-ITD+ AML生长所需的协同转录因子调控子。

RUNX1-ETO Depletion in t(8;21) AML Leads to C/EBPα- and AP-1-Mediated Alterations in Enhancer-Promoter Interaction

t(8;21) AML 中 RUNX1-ETO 的缺失导致 C/EBPα 和 AP-1 介导的增强子-启动子相互作用改变