Luke Isbel相关文献与解析，生知库 | 链接生命科学的每一步

Alicia K Michael #, Lisa Stoos #, Priya Crosby, Nikolas Eggers, Xinyu Y Nie, Kristina Makasheva, Martina Minnich, Kelly L Healy, Joscha Weiss, Georg Kempf, Simone Cavadini, Lukas Kater, Jan Seebacher, Luca Vecchia, Deyasini Chakraborty, Luke Isbel, Ralph S Grand, Florian Andersch, Jennifer L Fribour

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FCM

IHC-P

G3P

发表日期：2023

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ZFP462 safeguards neural lineage specification by targeting G9A/GLP-mediated heterochromatin to silence enhancers

ZFP462 通过靶向 G9A/GLP 介导的异染色质来沉默增强子，从而保障神经谱系规范

期刊:Nature Cell Biology

影响因子:17.3

doi:10.1038/s41556-022-01051-2

Ramesh Yelagandula #, Karin Stecher #, Maria Novatchkova, Luca Michetti, Georg Michlits, Jingkui Wang, Pablo Hofbauer, Gintautas Vainorius, Carina Pribitzer, Luke Isbel, Sasha Mendjan, Dirk Schübeler, Ulrich Elling, Julius Brennecke, Oliver Bell

Readout of histone methylation by Trim24 locally restricts chromatin opening by p53

Trim24 读取组蛋白甲基化可局部限制 p53 开放染色质

期刊:Nature Structural & Molecular Biology

影响因子:12.5

doi:10.1038/s41594-023-01021-8

Luke Isbel, Murat Iskar, Sevi Durdu, Joscha Weiss, Ralph S Grand, Eric Hietter-Pfeiffer, Zuzanna Kozicka, Alicia K Michael, Lukas Burger, Nicolas H Thomä, Dirk Schübeler

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发表日期：2023

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CG dinucleotides enhance promoter activity independent of DNA methylation

CG二核苷酸增强启动子活性，且该作用独立于DNA甲基化。

期刊:Genome Research

影响因子:6.2

doi:10.1101/gr.241653.118.

Dominik Hartl,Arnaud R Krebs,Ralph S Grand,Tuncay Baubec,Luke Isbel,Christiane Wirbelauer,Lukas Burger,Dirk Schübeler

DNA甲基化

发表日期：2019

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Wiz binds active promoters and CTCF-binding sites and is required for normal behaviour in the mouse

Wiz 结合活性启动子和 CTCF 结合位点，是小鼠正常行为所必需的

期刊:Elife

影响因子:6.4

doi:10.7554/eLife.15082

Luke Isbel, Lexie Prokopuk, Haoyu Wu, Lucia Daxinger, Harald Oey, Alex Spurling, Adam J Lawther, Matthew W Hale, Emma Whitelaw

Hypomethylation of ERVs in the sperm of mice haploinsufficient for the histone methyltransferase Setdb1 correlates with a paternal effect on phenotype

组蛋白甲基转移酶 Setdb1 单倍体不足的小鼠精子中 ERV 的低甲基化与父系对表型的影响相关

期刊:Scientific Reports

影响因子:3.8

doi:10.1038/srep25004

Lucia Daxinger, Harald Oey, Luke Isbel, Nadia C Whitelaw, Neil A Youngson, Alex Spurling, Kelly K D Vonk, Emma Whitelaw

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发表日期：2016

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The recently identified modifier of murine metastable epialleles, Rearranged L-Myc Fusion, is involved in maintaining epigenetic marks at CpG island shores and enhancers

最近发现的小鼠亚稳态表观等位基因修饰因子——重排的 L-Myc 融合，参与维持 CpG 岛岸的表观遗传标记和增强子

期刊:BMC Biology

影响因子:4.4

doi:10.1186/s12915-015-0128-2

Sarah K Harten, Harald Oey, Lauren M Bourke, Vandhana Bharti, Luke Isbel, Lucia Daxinger, Pierre Faou, Neil Robertson, Jacqueline M Matthews, Emma Whitelaw

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发表日期：2015

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Trim33 Binds and Silences a Class of Young Endogenous Retroviruses in the Mouse Testis; a Novel Component of the Arms Race between Retrotransposons and the Host Genome

Trim33 结合并抑制小鼠睾丸中一类年轻的内源性逆转录病毒；逆转录转座子与宿主基因组之间军备竞赛的新组成部分

期刊:PLoS Genetics

影响因子:

doi:10.1371/journal.pgen.1005693

Luke Isbel, Rahul Srivastava, Harald Oey, Alex Spurling, Lucia Daxinger, Hamsa Puthalakath, Emma Whitelaw

An ENU mutagenesis screen identifies novel and known genes involved in epigenetic processes in the mouse

ENU 诱变筛选可识别小鼠表观遗传过程中涉及的新基因和已知基因

期刊:Genome Biology

影响因子:10.1

doi:10.1186/gb-2013-14-9-r96

Lucia Daxinger, Sarah K Harten, Harald Oey, Trevor Epp, Luke Isbel, Edward Huang, Nadia Whitelaw, Anwyn Apedaile, Anabel Sorolla, Joan Yong, Vandhana Bharti, Joanne Sutton, Alyson Ashe, Zhenyi Pang, Nathan Wallace, Daniel J Gerhardt, Marnie E Blewitt, Jeffrey A Jeddeloh, Emma Whitelaw

Cooperation between bHLH transcription factors and histones for DNA access

bHLH 转录因子与组蛋白协作获取 DNA

ZFP462 safeguards neural lineage specification by targeting G9A/GLP-mediated heterochromatin to silence enhancers

ZFP462 通过靶向 G9A/GLP 介导的异染色质来沉默增强子，从而保障神经谱系规范

Readout of histone methylation by Trim24 locally restricts chromatin opening by p53

Trim24 读取组蛋白甲基化可局部限制 p53 开放染色质

CG dinucleotides enhance promoter activity independent of DNA methylation

CG二核苷酸增强启动子活性，且该作用独立于DNA甲基化。

Wiz binds active promoters and CTCF-binding sites and is required for normal behaviour in the mouse

Wiz 结合活性启动子和 CTCF 结合位点，是小鼠正常行为所必需的

Hypomethylation of ERVs in the sperm of mice haploinsufficient for the histone methyltransferase Setdb1 correlates with a paternal effect on phenotype

组蛋白甲基转移酶 Setdb1 单倍体不足的小鼠精子中 ERV 的低甲基化与父系对表型的影响相关

The recently identified modifier of murine metastable epialleles, Rearranged L-Myc Fusion, is involved in maintaining epigenetic marks at CpG island shores and enhancers

最近发现的小鼠亚稳态表观等位基因修饰因子——重排的 L-Myc 融合，参与维持 CpG 岛岸的表观遗传标记和增强子

Trim33 Binds and Silences a Class of Young Endogenous Retroviruses in the Mouse Testis; a Novel Component of the Arms Race between Retrotransposons and the Host Genome

Trim33 结合并抑制小鼠睾丸中一类年轻的内源性逆转录病毒；逆转录转座子与宿主基因组之间军备竞赛的新组成部分

An ENU mutagenesis screen identifies novel and known genes involved in epigenetic processes in the mouse

ENU 诱变筛选可识别小鼠表观遗传过程中涉及的新基因和已知基因