日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Somatic mutation and selection at population scale

群体尺度上的体细胞突变和选择

Lawson, Andrew R J; Abascal, Federico; Nicola, Pantelis A; Lensing, Stefanie V; Roberts, Amy L; Kalantzis, Georgios; Baez-Ortega, Adrian; Brzozowska, Natalia; El-Sayed Moustafa, Julia S; Vaitkute, Dovile; Jakupovic, Belma; Nessa, Ayrun; Wadge, Samuel; Österdahl, Marc F; Paterson, Anna L; Rassl, Doris M; Alcantara, Raul E; O'Neill, Laura; Widaa, Sara; Austin-Guest, Siobhan; Neville, Matthew D C; Przybilla, Moritz J; Cheng, Wei; Morra, Maria; Sykes, Lucy; Mayho, Matthew; Müller-Sienerth, Nicole; Williams, Nicholas; Alexander, Diana; Harvey, Luke M R; Clarke, Thomas; Byrne, Alex; Blundell, Jamie R; Young, Matthew D; Mahbubani, Krishnaa T A; Saeb-Parsy, Kourosh; Martin, Hilary C; Stratton, Michael R; Campbell, Peter J; Rahbari, Raheleh; Small, Kerrin S; Martincorena, Iñigo

Somatic mutation rates scale with lifespan across mammals

哺乳动物的体细胞突变率随寿命而变化。

Cagan, Alex; Baez-Ortega, Adrian; Brzozowska, Natalia; Abascal, Federico; Coorens, Tim H H; Sanders, Mathijs A; Lawson, Andrew R J; Harvey, Luke M R; Bhosle, Shriram; Jones, David; Alcantara, Raul E; Butler, Timothy M; Hooks, Yvette; Roberts, Kirsty; Anderson, Elizabeth; Lunn, Sharna; Flach, Edmund; Spiro, Simon; Januszczak, Inez; Wrigglesworth, Ethan; Jenkins, Hannah; Dallas, Tilly; Masters, Nic; Perkins, Matthew W; Deaville, Robert; Druce, Megan; Bogeska, Ruzhica; Milsom, Michael D; Neumann, Björn; Gorman, Frank; Constantino-Casas, Fernando; Peachey, Laura; Bochynska, Diana; Smith, Ewan St John; Gerstung, Moritz; Campbell, Peter J; Murchison, Elizabeth P; Stratton, Michael R; Martincorena, Iñigo

Inherited MUTYH mutations cause elevated somatic mutation rates and distinctive mutational signatures in normal human cells

遗传性 MUTYH 突变会导致正常人类细胞中体细胞突变率升高和独特的突变特征

Philip S Robinson, Laura E Thomas, Federico Abascal, Hyunchul Jung, Luke M R Harvey, Hannah D West, Sigurgeir Olafsson, Bernard C H Lee, Tim H H Coorens, Henry Lee-Six, Laura Butlin, Nicola Lander, Rebekah Truscott, Mathijs A Sanders, Stefanie V Lensing, Simon J A Buczacki, Rogier Ten Hoopen, Nichol