A new mouse line with reduced GluA2 Q/R site RNA editing exhibits loss of dendritic spines, hippocampal CA1-neuron loss, learning and memory impairments and NMDA receptor-independent seizure vulnerability
一种 GluA2 Q/R 位点 RNA 编辑减少的新型小鼠系表现出树突棘丢失、海马 CA1 神经元丢失、学习和记忆障碍以及 NMDA 受体独立的癫痫易感性
期刊:Molecular Brain
影响因子:3.3
doi:10.1186/s13041-020-0545-1
Lyndsey M Konen, Amanda L Wright, Gordon A Royle, Gary P Morris, Benjamin K Lau, Patrick W Seow, Raphael Zinn, Luke T Milham, Christopher W Vaughan, Bryce Vissel