日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

CasMiner: a deep-learning tool for high-throughput mining and rational design of efficient Cas9

CasMiner：一种用于高通量挖掘和高效Cas9合理设计的深度学习工具

期刊:National Science Review
影响因子:17.1
doi:10.1093/nsr/nwag090
Xu, Guoshun; Li, Suzhen; Li, Haoyu; Ren, Xiaopu; Ding, Yekun; Pang, Xinli; Liu, Xu; Tang, Qiaoling; Tu, Tao; Wang, Yuan; Luo, Huiying; Yao, Bin; Tian, Jian; Chen, Rumei; Guan, Feifei
发表日期：2026
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Synergistic Tuning of Conformational Dynamics, Electron Tunneling, and Substrate Positioning Enhances Electron Transfer in a P450 Chimera for Calcifediol Biosynthesis

构象动力学、电子隧穿和底物定位的协同调控增强了P450嵌合体中用于骨化二醇生物合成的电子转移

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202519381
Liang, Ziqi; Song, Xitong; Cheng, Shuming; Shen, Yiwen; Zhang, Jie; Wang, Yaru; Luo, Huiying; Yao, Bin; Wang, Binju; Tu, Tao
信号转导
发表日期：2026
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Revealing the intricate mechanism governing the pH-dependent activity of a quintessential representative of flavoproteins, glucose oxidase

揭示了控制黄素蛋白典型代表——葡萄糖氧化酶的pH依赖性活性的复杂机制

期刊:Fundamental Research
影响因子:6.3
doi:10.1016/j.fmre.2024.04.009
Tu, Tao; Zhang, Yunju; Yan, Yaru; Li, Lanxue; Liu, Xiaoqing; Hakulinen, Nina; Zhang, Wei; Mu, Yuguang; Luo, Huiying; Yao, Bin; Li, Weifeng; Huang, Huoqing
发表日期：2026
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Development and Application of a Cumate-Inducible Promoter, P(gc), in Komagataella pastoris

在毕赤酵母中开发和应用枯草杆菌蛋白酶诱导型启动子 P(gc)

期刊:Microbial Biotechnology
影响因子:5.2
doi:10.1111/1751-7915.70311
Xie, Jiachen; Xing, Yazhu; Luo, Huiying; Wang, Yuan; Zhang, Wei; Xu, Nan; Liu, Bo
发表日期：2026
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Engineering high-efficiency mutants of the transposase ISDra2 TnpB via protein-generative models and energy-optimized design

利用蛋白质生成模型和能量优化设计构建转座酶 ISDra2 TnpB 的高效突变体

期刊:aBIOTECH
影响因子:5
doi:10.1016/j.abiote.2026.100027
Guan, Feifei; Ding, Yekun; Xu, Guoshun; Fan, Lingxi; Gu, Xiaofeng; Wang, Yuan; Luo, Huiying; Yao, Bin; Tian, Jian
发表日期：2026
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Artificial intelligence-driven discovery of bioactive peptides: Computational approaches and future perspectives

人工智能驱动的生物活性肽发现：计算方法和未来展望

期刊:aBIOTECH
影响因子:5
doi:10.1016/j.abiote.2025.100014
Liu, Xu; Guan, Feifei; Luo, Huiying; Yao, Bin; Tian, Jian
发表日期：2026
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A combined strategy for high-efficiency expression of alkaline protease PrtA in Komagataella phaffii (syn. Pichia pastoris)

一种在毕赤酵母（Komagataella phaffii，同义词：Pichia pastoris）中高效表达碱性蛋白酶PrtA的联合策略

期刊:Microbial Cell Factories
影响因子:4.9
doi:10.1186/s12934-026-02978-z
Zhao, Baozhen; Zhou, Qiao; Wei, Panpan; Zhang, Honghai; Qin, Xing; Tu, Tao; Huang, Huoqing; Yao, Bin; Dong, Tao; Luo, Huiying
发表日期：2026
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Multistep metabolic engineering of Pichia pastoris for biosynthesis of N‑acetylneuraminic acid

利用毕赤酵母的多步代谢工程技术合成N-乙酰神经氨酸

期刊:Applied Microbiology and Biotechnology
影响因子:4.3
doi:10.1007/s00253-026-13744-x
Zhao, Xiaomin; Li, Qian; Luo, Huiying; Wang, Yuan; Xu, Xinxin; Zhang, Wei; Zhang, Jie; Liu, Bo
代谢
发表日期：2026
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DLFea4AMPGen de novo design of antimicrobial peptides by integrating features learned from deep learning models

DLFea4AMPGen 通过整合从深度学习模型中学习到的特征，从头设计抗菌肽

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-64378-y
Gao, Han; Guan, Feifei; Luo, Boyu; Zhang, Dongdong; Liu, Wei; Shen, Yuying; Fan, Lingxi; Xu, Guoshun; Wang, Yuan; Tu, Tao; Wu, Ningfeng; Yao, Bin; Luo, Huiying; Teng, Yue; Tian, Jian; Huang, Huoqing
发表日期：2025
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Effective Gene Expression Prediction and Optimization from Protein Sequences

基于蛋白质序列的有效基因表达预测与优化

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202407664
Liu, Tuoyu; Zhang, Yiyang; Li, Yanjun; Xu, Guoshun; Gao, Han; Wang, Pengtao; Tu, Tao; Luo, Huiying; Wu, Ningfeng; Yao, Bin; Liu, Bo; Guan, Feifei; Huang, Huoqing; Tian, Jian
发表日期：2025
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