日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Correction: USP20 positively regulates tumorigenesis and chemoresistance through β-catenin stabilization

更正：USP20 通过 β-catenin 稳定作用正向调控肿瘤发生和化疗耐药性

期刊:Cell Death and Differentiation
影响因子:15.4
doi:10.1038/s41418-025-01593-6
Wu, Chenming; Luo, Kuntian; Zhao, Fei; Yin, Ping; Song, Ying; Deng, Min; Huang, Jinzhou; Chen, Yuping; Li, Lei; Lee, SeungBaek; Kim, JungJin; Zhou, Qin; Tu, Xinyi; Nowsheen, Somaira; Luo, Qifeng; Gao, Xiumei; Lou, Zhenkun; Liu, Zhongmin; Yuan, Jian
信号转导
肿瘤
肿瘤免疫
发表日期：2026
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KCTD10 is a sensor for co-directional transcription-replication conflicts

KCTD10 是一种用于检测同向转录-复制冲突的传感器

期刊:Nature
影响因子:48.5
doi:10.1038/s41586-025-09585-9
Kloeber, Jake A; Chen, Bin; Sun, Guangchao; King, Charles S; Wang, Zhiquan; Wang, Li; Wu, Zheming; Zhu, Shouhai; Zhao, Fei; Qin, Hongran; Ouyang, Yaobin; Xiao, Huaping; Tu, Xinyi; Lu, Jing; Jiang, Yanxia; Luo, Kuntian; Yin, Ping; Wu, Xinyan; Mutter, Robert W; Huang, Jinzhou; Lou, Zhenkun
发表日期：2025
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Parkin deficiency promotes colorectal tumorigenesis and progression through RIPK3-dependent necroptotic inflammation

Parkin 缺陷通过 RIPK3 依赖性坏死性炎症促进结直肠肿瘤的发生和发展。

期刊:Cancer Communications
影响因子:24.9
doi:10.1002/cac2.12648
Wu, Zheming; Xiao, Huaping; Kloeber, Jake A; Ouyang, Yaobin; Yin, Ping; Huang, Jinzhou; Chen, Bin; Zhu, Shouhai; Lu, Jing; Han, Yiqun; Tu, Xinyi; Dragojevic, Sonja; Luo, Kuntian; Ting, Adrian T; Welliver, Meng; Lou, Zhenkun
RIPK3
肿瘤
炎症
肿瘤免疫
炎症/感染
Parkin
RIP
发表日期：2025
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Isoform-specific function of NSD3 in DNA replication stress confers resistance to PARP inhibitors in prostate cancer.

NSD3 在 DNA 复制压力中的亚型特异性功能赋予前列腺癌细胞对 PARP 抑制剂的耐药性

期刊:Molecular Cell
影响因子:16.6
doi:10.1016/j.molcel.2025.06.004
Zhu Shouhai, Gao Huanyao, Jiang Dan, Guo Guijie, Hou Jing, Han Yiqun, Zhang Chao, Hu Xiaoping, Indulkar Shreya, Kloeber Jake A, Hu Qi, Jiang Yanxia, Zeng Xiangyu, Ouyang Yaobin, Lu Jing, Yin Ping, Luo Kuntian, Huang Jinzhou, Wu Zheming, Chen Bin, Xiao Huaping, Dragojevic Sonja, Qin Hongran, Zhou Xiang, Jin Jian, Tu Xinyi, Wang Liewei, Lou Zhenkun
细胞生物学
肿瘤免疫
发表日期：2025
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Syk-dependent homologous recombination activation promotes cancer resistance to DNA targeted therapy.

Syk依赖的同源重组激活促进癌症对DNA靶向治疗的耐药性

期刊:Drug Resistance Updates
影响因子:21.7
doi:10.1016/j.drup.2024.101085
Zhou Qin, Tu Xinyi, Hou Xiaonan, Yu Jia, Zhao Fei, Huang Jinzhou, Kloeber Jake, Olson Anna, Gao Ming, Luo Kuntian, Zhu Shouhai, Wu Zheming, Zhang Yong, Sun Chenyu, Zeng Xiangyu, Schoolmeester Kenneth J, Weroha John S, Hu Xiwen, Jiang Yanxia, Wang Liewei, Mutter Robert W, Lou Zhenkun
肿瘤
肿瘤免疫
发表日期：2024
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Correction to: USP20 positively regulates tumorigenesis and chemoresistance through β-catenin stabilization

更正：USP20 通过 β-catenin 稳定作用正向调控肿瘤发生和化疗耐药性

期刊:Cell Death and Differentiation
影响因子:15.4
doi:10.1038/s41418-022-01079-9
Wu, Chenming; Luo, Kuntian; Zhao, Fei; Yin, Ping; Song, Ying; Deng, Min; Huang, Jinzhou; Chen, Yuping; Li, Lei; Lee, SeungBaek; Kim, JungJin; Zhou, Qin; Tu, Xinyi; Nowsheen, Somaira; Luo, Qifeng; Gao, Xiumei; Lou, Zhenkun; Liu, Zhongmin; Yuan, Jian
信号转导
肿瘤
肿瘤免疫
发表日期：2023
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Author Correction: The bromodomain containing protein BRD-9 orchestrates RAD51-RAD54 complex formation and regulates homologous recombination-mediated repair

作者更正：含溴结构域蛋白BRD-9协调RAD51-RAD54复合物的形成并调节同源重组介导的修复。

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-022-35058-y
Zhou, Qin; Huang, Jinzhou; Zhang, Chao; Zhao, Fei; Kim, Wootae; Tu, Xinyi; Zhang, Yong; Nowsheen, Somaira; Zhu, Qian; Deng, Min; Chen, Yuping; Qin, Bo; Luo, Kuntian; Liu, Baohua; Lou, Zhenkun; Mutter, Robert W; Yuan, Jian
RAD51
RAD54
发表日期：2022
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A novel UCHL(3) inhibitor, perifosine, enhances PARP inhibitor cytotoxicity through inhibition of homologous recombination-mediated DNA double strand break repair

一种新型UCHL(3)抑制剂perifosine，通过抑制同源重组介导的DNA双链断裂修复，增强PARP抑制剂的细胞毒性。

期刊:Cell Death & Disease
影响因子:9.6
doi:10.1038/s41419-019-1628-8
Song, Zhiwang; Tu, Xinyi; Zhou, Qin; Huang, Jinzhou; Chen, Yuping; Liu, Jiaqi; Lee, SeungBaek; Kim, Wootae; Nowsheen, Somaira; Luo, Kuntian; Yuan, Jian; Lou, Zhenkun
PARP
细胞生物学
毒理研究
发表日期：2019
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A divergent role of the SIRT1-TopBP1 axis in regulating metabolic checkpoint and DNA damage checkpoint

SIRT1-TopBP1轴在调节代谢检查点和DNA损伤检查点中发挥不同的作用

期刊:Molecular Cell
影响因子:16.6
doi:10.1016/j.molcel.2014.10.007
Liu, Tongzheng; Lin, Yi-Hui; Leng, Wenchuan; Jung, Sung Yun; Zhang, Haoxing; Deng, Min; Evans, Debra; Li, Yunhui; Luo, Kuntian; Qin, Bo; Qin, Jun; Yuan, Jian; Lou, Zhenkun
毒理研究
代谢
发表日期：2014
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Sumoylation of MDC1 is important for proper DNA damage response

MDC1的SUMO化对于正常的DNA损伤反应至关重要。

期刊:EMBO Journal
影响因子:8.3
doi:10.1038/emboj.2012.158
Luo, Kuntian; Zhang, Haoxing; Wang, Liewei; Yuan, Jian; Lou, Zhenkun
SUMO
MDC1
毒理研究
MDC
发表日期：2012
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