Luo Renhe相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

A Genetically Engineered Human Organoid Model Reveals Distinct Genetic and Epigenetic Barriers of Lineage Plasticity in Early PDAC Transformation

基因工程改造的人类类器官模型揭示了早期胰腺导管腺癌转化过程中谱系可塑性的独特遗传和表观遗传屏障

doi:10.64898/2026.03.09.710586

Zhang, Xian; Wong, Wilfred; Cho, Hyein S; Yang, Dapeng; Dixon, Gary; Luo, Renhe; Liu, Dingyu; Torre, Denis; Umeda, Shigeaki; González, Federico; Askan, Gokce; Yavas, Aslihan; Damodaran, Jeyaram Ravichandran; Rickert, Robert W; Kappagantula, Rajya; Pan, Fong Cheng; Aveson, Victoria G; Grimont, Adrien; Pulecio, Julian; Kaplan, Samuel J; Pan, Heng; Leach, Steven D; Iacobuzio-Donahue, Christine A; Chandwani, Rohit; Leslie, Christina S; Huangfu, Danwei

发表日期：2026

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FourC: identifying significant and differential contacts in 1D chromatin conformation data

FourC：识别一维染色质构象数据中的显著和差异性接触

doi:10.64898/2026.03.05.709811

Wong, Wilfred; Kaplan, Samuel J; Luo, Renhe; Pulecio, Julian; Yan, Jielin; Huangfu, Danwei; Leslie, Christina S

发表日期：2026

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Author Correction: ChromaFold predicts the 3D contact map from single-cell chromatin accessibility

作者更正：ChromaFold 通过单细胞染色质可及性预测 3D 接触图。

期刊:Nature Communications

影响因子:15.7

doi:10.1038/s41467-025-56017-3

Gao, Vianne R; Yang, Rui; Das, Arnav; Luo, Renhe; Luo, Hanzhi; McNally, Dylan R; Karagiannidis, Ioannis; Rivas, Martin A; Wang, Zhong-Min; Barisic, Darko; Karbalayghareh, Alireza; Wong, Wilfred; Zhan, Yingqian A; Chin, Christopher R; Noble, William S; Bilmes, Jeff A; Apostolou, Effie; Kharas, Michael G; Béguelin, Wendy; Viny, Aaron D; Huangfu, Danwei; Rudensky, Alexander Y; Melnick, Ari M; Leslie, Christina S

细胞生物学

发表日期：2025

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Discovery of NANOG enhancers and their essential roles in self-renewal and differentiation in human embryonic stem cells.

NANOG增强子的发现及其在人类胚胎干细胞自我更新和分化中的关键作用

期刊:Stem Cell Reports

影响因子:5.1

doi:10.1016/j.stemcr.2025.102511

Yan Jielin, Luo Renhe, Rosen Bess P, Liu Dingyu, Wong Wilfred, Leslie Christina S, Huangfu Danwei

发育与干细胞

细胞生物学

发表日期：2025

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Perturb-seq reveals distinct responses to pluripotency regulator dosages underlying the control of self-renewal and differentiation

Perturb-seq 揭示了多能性调节因子剂量对自我更新和分化调控的不同影响

doi:10.1101/2025.08.07.669196

Yan, Jielin; Cho, Hyein S; Luo, Renhe; Beer, Michael A; Li, Wei; Huangfu, Danwei

发表日期：2025

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A stem cell knockout village reveals lineage rewiring and a non-canonical islet cell fate in monogenic diabetes.

干细胞敲除实验揭示了单基因糖尿病中的谱系重编程和非典型胰岛细胞命运。

doi:10.64898/2025.12.23.696311

Liu Dingyu, Song Bicna, Li Zhaoheng, Zhang Stephen, Fabiha Tabassum, Zhao Jiahui, Inoki Ayaka, Piccand Julie, Soh Chew-Li, Dixon Gary, Zhong Aaron, Hu Nan, Luo Renhe, Ozlusen Batu, Menon Vipin, Zhou Ting, Qiu Xiaojie, Gradwohl Gerard, Yang Dapeng, Dey Kushal, Sun Wei, Li Wei, Huangfu Danwei

发育与干细胞

细胞生物学

发表日期：2025

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Dynamic network-guided CRISPRi screen reveals CTCF loop-constrained nonlinear enhancer-gene regulatory activity in cell state transitions

动态网络引导的CRISPRi筛选揭示了CTCF环约束的非线性增强子-基因调控活性在细胞状态转变中的作用

doi:10.1101/2023.03.07.531569

Luo, Renhe; Yan, Jielin; Oh, Jin Woo; Xi, Wang; Shigaki, Dustin; Wong, Wilfred; Cho, Hyunwoo; Murphy, Dylan; Cutler, Ronald; Rosen, Bess P; Pulecio, Julian; Yang, Dapeng; Glenn, Rachel; Chen, Tingxu; Li, Qing V; Vierbuchen, Thomas; Sidoli, Simone; Apostolou, Effie; Huangfu, Danwei; Beer, Michael A

细胞生物学

发表日期：2023

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Discovery of Competent Chromatin Regions in Human Embryonic Stem Cells

人类胚胎干细胞中具有功能能力的染色质区域的发现

doi:10.1101/2023.06.14.544990

Pulecio, Julian; Tayyebi, Zakieh; Liu, Dingyu; Wong, Wilfred; Luo, Renhe; Damodaran, Jeyaram R; Kaplan, Samuel; Cho, Hyunwoo; Yan, Jielin; Murphy, Dylan; Rickert, Robert W; Shukla, Abhijit; Zhong, Aaron; González, Federico; Yang, Dexin; Li, Wenbo; Zhou, Ting; Apostolou, Effie; Leslie, Christina S; Huangfu, Danwei

发育与干细胞

细胞生物学

发表日期：2023

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