日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Brain-derived neurotrophic factor and the derived dodecapeptide function as Toll-like receptor 4 antagonists in acute lung injury

脑源性神经营养因子及其衍生的十二肽在急性肺损伤中发挥Toll样受体4拮抗剂的作用

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-026-69541-7
Zhu, Weiwei; Jin, Leiming; Zhang, Qianhui; Cui, Yaqian; Zou, Yu; Chen, Pan; Ye, Jiaxi; Xiong, Yongqiang; Lin, Mengsha; Zhou, Yongqiang; Wu, Renlv; Liang, Yan; Zhuang, Zaishou; Huh, Joo Young; Luo, Wu; Liang, Guang
信号转导
神经科学
发表日期：2026
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Intermittent energy restriction and risk of physician-diagnosed diabetes progression: a propensity-weighted real-world cohort study

间歇性能量限制与医生诊断的糖尿病进展风险：一项倾向性加权真实世界队列研究

期刊:Frontiers in Nutrition
影响因子:5.1
doi:10.3389/fnut.2026.1744017
Xiao, Zhiyong; Zhou, Xu; Yang, Dongliang; Lai, Xihu; Zhang, Yewu; Wu, Ruiyu; Wang, Huiqing; Zhou, Jiali; Yang, Xiao; Xu, Feng; Luo, Wu; Chen, Xuan; Zhou, Bin; Yin, Xinhong; Liu, Dongbo
糖尿病
代谢
发表日期：2026
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Lumican-TLR4 interaction accelerates hepatic fibrosis by activating hepatic stellate cells

Lumican-TLR4相互作用通过激活肝星状细胞加速肝纤维化。

期刊:Hepatology Communications
影响因子:4.6
doi:10.1097/HC9.0000000000000948
Xiong, Yongqiang; Zhang, Huanhuan; Wang, Ao; Cui, Yaqian; Ye, Jiaxi; Jin, Leiming; Lin, Mengsha; Zhang, Qianhui; Liang, Guang; Luo, Wu; Zhu, Weiwei; Hu, Xiang
TLR4
细胞生物学
发表日期：2026
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Phenotype-specific association of C-reactive protein-to-lymphocyte ratio with incident proteinuric CKD versus isolated eGFR decline: a real-world retrospective cohort study

C反应蛋白/淋巴细胞比值与新发蛋白尿性慢性肾脏病和单纯eGFR下降的表型特异性关联：一项真实世界回顾性队列研究

期刊:Frontiers in Endocrinology
影响因子:4.6
doi:10.3389/fendo.2026.1769059
Yang, Wenbo; Jiang, Wen; Zhu, Qing; Wang, Mengru; Mulalibieke, Heizhati; Qin, Luo; Wu, Ting; Guo, Bingxuan; Hong, Jing; Li, Nanfang
细胞生物学
发表日期：2026
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Transmission dynamics and control of tuberculosis in high-altitude regions: a modelling study in Xizang, China

中国西藏高原地区结核病传播动力学及防控：一项建模研究

期刊:BMJ Open
影响因子:2.3
doi:10.1136/bmjopen-2025-112198
Li, Miaomiao; Zheng, Ruyu; Guo, Luo; Wu, Yuxuan; Dong, Jingran; Jiang, Hongxia; Song, Desheng; Cui, Zhuang; Li, Changping
发表日期：2026
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A mild and practical approach to N-CF(3) secondary amines via oxidative fluorination of isocyanides

通过异氰化物的氧化氟化反应，温和而实用地合成 N-CF(3) 仲胺

期刊:Nature Communications
影响因子:15.7
doi:10.1038/s41467-025-60225-2
Fu, Jia-Luo; Wu, Jun-Yunzi; Shi, Juan-Fen; Huang, Long-Ling; Wang, Honggen; Li, Qingjiang
发表日期：2025
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USP25 directly interacts with and deubiquitinates PPARα to increase PPARα stability in hepatocytes and attenuate high-fat diet-induced MASLD in mice.

USP25 直接与 PPARα 相互作用并使其去泛素化，从而增加肝细胞中 PPARα 的稳定性，并减轻高脂饮食诱导的小鼠 MASLD

期刊:Cell Death and Differentiation
影响因子:15.4
doi:10.1038/s41418-025-01444-4
Jin Leiming, Zhu Weiwei, Hu Xiang, Ye Lin, Lou Shuaijie, Zhang Qianhui, Wang Minxiu, Ye Bozhi, Min Julian, Wang Yi, Huang Lijiang, Luo Wu, Liang Guang
细胞生物学
泛素化
发表日期：2025
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Deubiquitinase OTUD6A alleviates acetaminophen-induced liver injury by targeting EZH2 to reduce cell death in hepatocytes.

去泛素化酶 OTUD6A 通过靶向 EZH2 来减少肝细胞死亡，从而减轻对乙酰氨基酚引起的肝损伤。

期刊:Acta Pharmaceutica Sinica B
影响因子:14.6
doi:10.1016/j.apsb.2025.06.027
Zhao Yanni, Jin Tianyang, Xu Tingxin, Fang Yi, Zheng Qingsong, Luo Wu, Zhu Weiwei, Chen Yue, Wang Jiong, Chen Yi, Zuo Wei, Huang Lijiang, Liang Guang, Wang Yi
表观遗传
泛素化
肝损伤
EZH2
细胞生物学
毒理研究
发表日期：2025
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Deubiquitinase JOSD2 alleviates colitis by inhibiting inflammation via deubiquitination of IMPDH2 in macrophages.

去泛素化酶 JOSD2 通过去泛素化巨噬细胞中的 IMPDH2 来抑制炎症，从而缓解结肠炎

期刊:Acta Pharmaceutica Sinica B
影响因子:14.6
doi:10.1016/j.apsb.2024.12.012
Liu Xin, Fang Yi, Huang Mincong, Tu Shiliang, Zheng Boan, Yuan Hang, Yu Peng, Lan Mengyao, Luo Wu, Zhou Yongqiang, Chen Guorong, Shen Zhe, Wang Yi, Liang Guang
细胞生物学
肠炎
巨噬细胞
泛素化
炎症
发表日期：2025
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Macrophage WEE1 Directly Binds to and Phosphorylates NF-κB p65 Subunit to Induce Inflammatory Response and Drive Atherosclerosis.

巨噬细胞 WEE1 直接结合并磷酸化 NF-κB p65 亚基，从而诱导炎症反应并驱动动脉粥样硬化

期刊:Advanced Science
影响因子:14.1
doi:10.1002/advs.202503192
Huang Zhuqi, Shen Sirui, Li Weixin, Wang Mengyang, Yang Yudie, Luo Wu, Han Xue, Xu Zheng, Min Julian, Long Xiaohong, Huang Weijian, Wu Gaojun, Wang Yi, Liang Guang
细胞生物学
动脉粥样硬化
巨噬细胞
炎症
磷酸化
发表日期：2025
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