日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Empagliflozin enhances metabolic efficiency and improves left ventricular hypertrophy in a hypertrophic cardiomyopathy mouse model

恩格列净可提高代谢效率并改善肥厚型心肌病小鼠模型中的左心室肥厚。

期刊:European Heart Journal
影响因子:35.6
doi:10.1093/eurheartj/ehaf324
Baka, Tomas; Moore, Jarrod; Qin, Fuzhong; Yurista, Salva R; Zhang, Aifeng; He, Huamei; Chambers, Jordan M; Croteau, Dominique; Goel, Raghuveera K; Smith, Hunter; Wang, Miranda C; Chen, Christopher S; Hobai, Ion A; Rombaldova, Martina; Kuda, Ondrej; Tardiff, Jil C; Balschi, James A; Pimentel, David R; Seidman, Christine E; Seidman, Jonathan G; Emili, Andrew; Colucci, Wilson S; Luptak, Ivan
心血管
心肌病
代谢
发表日期：2025
文献求助 收藏

SGLT2 inhibitor upregulates myocardial genes for oxidative phosphorylation and fatty acid metabolism in Gαq-mice.

SGLT2 抑制剂可上调 Gαq 小鼠心肌氧化磷酸化和脂肪酸代谢相关基因

期刊:Journal of Molecular and Cellular Cardiology Plus
影响因子:2.2
doi:10.1016/j.jmccpl.2025.100296
Chambers Jordan M, Croteau Dominique, Pimentel David R, Gower Adam C, Panagia Marcello, Baka Tomas, Qin Fuzhong, Luptak Ivan, Colucci Wilson S
代谢
磷酸化
发表日期：2025
文献求助 收藏

Hyperpolarized [1-(13)C] pyruvate MRSI reveals a diet-dependent metabolic shift in ZSF1 rats

超极化[1-(13)C]丙酮酸MRSI揭示了ZSF1大鼠饮食依赖性的代谢转变

期刊:Journal of Magnetic Resonance Open
影响因子:
doi:10.1016/j.jmro.2025.100205
Santos, Karen Dos; Yurista, Salva R; Mirrione, Sophia M; Bedoya, David O Guarin; Calos, Samuel R; Luptak, Ivan; Takahashi, Atsushi M; Tang, Wai Hong Wilson; Iwamoto, Yoshiko; Nguyen, Christopher T; Yen, Yi-Fen
Rat
代谢
发表日期：2025
文献求助 收藏

SGLT2 inhibitor ertugliflozin decreases elevated intracellular sodium, and improves energetics and contractile function in diabetic cardiomyopathy

SGLT2抑制剂艾格列净可降低升高的细胞内钠浓度，并改善糖尿病心肌病患者的能量代谢和收缩功能。

期刊:Biomedicine & Pharmacotherapy
影响因子:7.5
doi:10.1016/j.biopha.2023.114310
Croteau, Dominique; Baka, Tomas; Young, Sara; He, Huamei; Chambers, Jordan M; Qin, Fuzhong; Panagia, Marcello; Pimentel, David R; Balschi, James A; Colucci, Wilson S; Luptak, Ivan
SGLT2
心肌病
心血管
代谢
糖尿病
细胞生物学
发表日期：2023
文献求助 收藏

Hemodynamic testing to guide vasodilator therapy in cardiac amyloidosis

血流动力学检查指导心脏淀粉样变性血管扩张剂治疗

期刊:Journal of Cardiology Cases
影响因子:
doi:10.1016/j.jccase.2023.04.011
Rucker, Dane M; Siddiqi, Omar K; Pimentel, David R; Luptak, Ivan
发表日期：2023
文献求助 收藏

Novel Small-Molecule Troponin Activator Increases Cardiac Contractile Function Without Negative Impact on Energetics

新型小分子肌钙蛋白激活剂可增强心脏收缩功能，且不影响能量代谢。

期刊:Circulation-Heart Failure
影响因子:8.4
doi:10.1161/CIRCHEARTFAILURE.121.009195
He, Huamei; Baka, Tomas; Balschi, James; Motani, Alykhan S; Nguyen, Kathy K; Liu, Qingxiang; Slater, Rebecca; Rock, Brooke; Wang, Chen; Hale, Christopher; Karamanlidis, Georgios; Hartman, James J; Malik, Fady I; Reagan, Jeff D; Luptak, Ivan
代谢
发表日期：2022
文献求助 收藏

Effects of Sodium-Glucose Linked Transporter 2 Inhibition With Ertugliflozin on Mitochondrial Function, Energetics, and Metabolic Gene Expression in the Presence and Absence of Diabetes Mellitus in Mice

埃格列净抑制钠-葡萄糖协同转运蛋白2对糖尿病小鼠线粒体功能、能量代谢和代谢基因表达的影响

期刊:Journal of the American Heart Association
影响因子:5.3
doi:10.1161/JAHA.120.019995
Croteau, Dominique; Luptak, Ivan; Chambers, Jordan M; Hobai, Ion; Panagia, Marcello; Pimentel, David R; Siwik, Deborah A; Qin, Fuzhong; Colucci, Wilson S
糖尿病
线粒体
代谢
发表日期：2021
文献求助 收藏

Redox-Resistant SERCA [Sarco(endo)plasmic Reticulum Calcium ATPase] Attenuates Oxidant-Stimulated Mitochondrial Calcium and Apoptosis in Cardiac Myocytes and Pressure Overload-Induced Myocardial Failure in Mice

抗氧化还原SERCA [肌浆网（内质网）钙ATP酶]可减弱氧化剂刺激的心肌细胞线粒体钙和细胞凋亡，并减轻小鼠压力超负荷诱导的心肌衰竭

期刊:Circulation
影响因子:38.6
doi:10.1161/CIRCULATIONAHA.120.048183
Goodman, Jena B; Qin, Fuzhong; Morgan, Robert J; Chambers, Jordan M; Croteau, Dominique; Siwik, Deborah A; Hobai, Ion; Panagia, Marcello; Luptak, Ivan; Bachschmid, Markus; Tong, XiaoYong; Pimentel, David R; Cohen, Richard A; Colucci, Wilson S
凋亡
表观遗传
Apoptosis
线粒体
细胞生物学
发表日期：2020
文献求助 收藏

Role of Glutaredoxin-1 and Glutathionylation in Cardiovascular Diseases

谷胱甘肽还原酶-1和谷胱甘肽化在心血管疾病中的作用

期刊:International Journal of Molecular Sciences
影响因子:4.9
doi:10.3390/ijms21186803
Burns, Mannix; Rizvi, Syed Husain Mustafa; Tsukahara, Yuko; Pimentel, David R; Luptak, Ivan; Hamburg, Naomi M; Matsui, Reiko; Bachschmid, Markus M
心血管疾病
心血管
发表日期：2020
文献求助 收藏

Increasing mitochondrial ATP synthesis with butyrate normalizes ADP and contractile function in metabolic heart disease

丁酸盐增加线粒体ATP合成可使代谢性心脏病患者的ADP水平和收缩功能恢复正常。

期刊:NMR in Biomedicine
影响因子:2.7
doi:10.1002/nbm.4258
Panagia, Marcello; He, Huamei; Baka, Tomas; Pimentel, David R; Croteau, Dominique; Bachschmid, Markus M; Balschi, James A; Colucci, Wilson S; Luptak, Ivan
心脏病
线粒体
心血管
代谢
发表日期：2020
文献求助 收藏