MEK Inhibition Sensitizes Pancreatic Cancer to STING Agonism by Tumor Cell-intrinsic Amplification of Type I IFN Signaling.
MEK 抑制剂通过肿瘤细胞内在的 I 型 IFN 信号放大作用，使胰腺癌对 STING 激动剂更加敏感
期刊:Clinical Cancer Research
影响因子:10.2
doi:10.1158/1078-0432.CCR-22-3322
Ghukasyan Razmik, Liang Keke, Chau Kevin, Li Luyi, Chan Charlotte, Abt Evan R, Le Thuc, Park Joon Y, Wu Nanping, Premji Alykhan, Damoiseaux Robert, Luu Tony, Labora Amanda, Rashid Khalid, Link Jason M, Radu Caius G, Donahue Timothy R
