日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Mitochondrial PDHA1 acetylation orchestrates lactate-dependent epigenetic reprogramming to promote fibrosis via NUAK2

线粒体PDHA1乙酰化通过NUAK2调控乳酸依赖性表观遗传重编程，从而促进纤维化。

期刊:Cellular and Molecular Life Sciences
影响因子:6.2
doi:10.1007/s00018-026-06166-5
Wang, Yujie; Du, Guanglian; Zhang, Jinjin; Zhai, Nailiang; Liu, Weili; Cao, Guohong; Li, Hongbo; Liu, Bo; Yang, Huiling; Lv, Changjun; Song, Xiaodong; Zhang, Songzi
信号转导
乙酰化
线粒体
表观遗传
发表日期：2026
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Recombinant SARS-Cov-2 spike protein S1 subunit upregulates P2 × 7-NLRP3 leading to macrophage pyroptosis promoting acute lung injury.

重组 SARS-Cov-2 刺突蛋白 S1 亚基上调 P2Â×Â7-NLRP3，导致巨噬细胞焦亡，从而促进急性肺损伤。

期刊:Respiratory Research
影响因子:5
doi:10.1186/s12931-026-03513-9
Lu Manlu, Li Mingzhen, Zhou Huijie, Zhu Jiwei, Jiao Qianqian, Liu Xiaojing, Wu Jinglin, Xu Guogang, Lv Changjun, Fan Yichu, Zhang Bin, Pan Lei
巨噬细胞
表观遗传
巨噬细胞
LRP3
焦亡
NLRP3
细胞生物学
免疫/内分泌
发表日期：2026
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YTHDC1 phase separation drives the nuclear export of m(6)A-modified lncNONMMUT062668.2 through the transport complex SRSF3-ALYREF-XPO5 to aggravate pulmonary fibrosis.

YTHDC1 相分离驱动 m(6)A 修饰的 lncNONMMUT062668.2 通过转运复合物 SRSF3-ALYREF-XPO5 输出到细胞核，从而加剧肺纤维化

期刊:Cell Death & Disease
影响因子:9.6
doi:10.1038/s41419-025-07608-x
Chen Shengjun, Wang Yujie, Zhang Jinjin, Liu Bo, Liu Weili, Cao Guohong, Li Rongrong, Li Hongbo, Zhai Nailiang, Song Xiaodong, Zhang Songzi, Lv Changjun
细胞生物学
发表日期：2025
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Detecting microsatellite instability in cancer via multiplexed orthogonal gap-enhanced Raman tags

利用多重正交间隙增强拉曼标签检测癌症中的微卫星不稳定性

期刊:Chemical Science
影响因子:7.4
doi:10.1039/d5sc01912e
Fu, Guowei; Li, Jin; Zhang, Qian; Lv, Changjun; Zhang, Zhiyang; Wang, Xiaoyan; Wu, Rihui; Chen, Lingxin
肿瘤
肿瘤免疫
发表日期：2025
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Molecular mechanisms of α-syn abnormal phase separation in cognitive impairment induced by chronic intermittent hypoxia and the neuroprotective effects of Danshensu methyl ester.

慢性间歇性缺氧引起的认知障碍中α-syn异常相分离的分子机制及丹参素甲酯的神经保护作用。

期刊:Molecular Medicine
影响因子:6.4
doi:10.1186/s10020-025-01366-4
Li Juan, Zhang Na, Zhang Ziyin, Fu Jinsai, Ren Wenjing, Sun Yi, Song Shuling, Liu Xiaoqian, Liu Jinghui, Wang Jingyu, Sun Yunliang, Zhang Kai, Guo Rongrong, Lv Changjun, Pan Lei, Qu Guiwu, Han Fang, Yu Yan
神经科学
相分离
发表日期：2025
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STAT3 Facilitates Super Enhancer Formation to Promote Fibroblast-To-Myofibroblast Differentiation by the Analysis of ATAC-Seq, RNA-Seq and ChIP-Seq

通过ATAC-Seq、RNA-Seq和ChIP-Seq分析发现，STAT3促进超级增强子形成，从而促进成纤维细胞向肌成纤维细胞分化。

期刊:Journal of Cellular and Molecular Medicine
影响因子:4.2
doi:10.1111/jcmm.70639
Wang, Yujie; Zhao, Yaqin; Cao, Guohong; Jiang, Mengqi; Yuan, Xinglong; Li, Hongbo; Song, Xiaodong; Zhang, Jinjin; Lv, Changjun; Zhang, Songzi
JAK/STAT
成纤维细胞
细胞生物学
STAT3
发表日期：2025
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Obstructive sleep apnea in community-dwelling polio survivors: a 5-year longitudinal follow-up study

社区居住的小儿麻痹症幸存者阻塞性睡眠呼吸暂停：一项为期5年的纵向随访研究

期刊:Frontiers in Neurology
影响因子:2.8
doi:10.3389/fneur.2025.1643862
Ding, Qidi; Li, Xiao; Wang, Meng; Wang, Jingyu; Sun, Ting; Sun, Yunliang; Liu, Jianghua; Yu, Yan; Wu, Jinxian; Du, Juan; Dong, Xiaosong; Zhang, Chi; Zuo, Yuhua; Zhao, Long; Li, Jing; Lv, Changjun; Strohl, Kingman P; Han, Fang
发表日期：2025
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Three-dimensional cultured human umbilical cord mesenchymal stem cells attenuate pulmonary fibrosis by improving the balance of mitochondrial fusion and fission

三维培养的人脐带间充质干细胞通过改善线粒体融合与分裂的平衡来减轻肺纤维化

期刊:Stem Cells Translational Medicine
影响因子:4.9
doi:10.1093/stcltm/szae051
Zhai, Huifang; Jiang, Mengqi; Zhao, Yaqin; Wang, Yujie; Zhang, Haitong; Ji, Yunxia; Song, Xiaodong; Zhang, Jinjin; Lv, Changjun; Li, Minge
细胞生物学
发育与干细胞
线粒体
干细胞
发表日期：2024
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circELP2 reverse-splicing biogenesis and function as a pro-fibrogenic factor by targeting mitochondrial quality control pathway

circELP2通过靶向线粒体质量控制通路，参与其逆向剪接的生物合成并发挥促纤维化因子的作用

期刊:Journal of Cellular and Molecular Medicine
影响因子:4.2
doi:10.1111/jcmm.18098
Zhang, Songzi; Tu, Diwei; Liu, Weili; Li, Ruiqiong; Jiang, Mengqi; Yuan, Xinglong; Luan, Jianlin; Li, Hongbo; Lv, Changjun; Song, Xiaodong
信号转导
线粒体
发表日期：2024
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Circ_0044235 regulates the development of osteoarthritis by the modulation of miR-375/PIK3R3 axis

Circ_0044235 通过调节 miR-375/PIK3R3 轴来调控骨关节炎的发展

期刊:Journal of Orthopaedic Surgery and Research
影响因子:2.8
doi:10.1186/s13018-024-04694-z
Wenjie Qian, Kai Mei, Lei Zhu, Ying Chu, Jinpeng Lv, Changjun Yun
免疫
关节炎
发表日期：2024
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