Mannose inhibits PKM2 lactylation to induce pyroptosis in bladder cancer and activate antitumor immune responses
甘露糖抑制PKM2乳酸化，从而诱导膀胱癌细胞焦亡并激活抗肿瘤免疫反应。
期刊:Communications Biology
影响因子:5.1
doi:10.1038/s42003-025-08130-8
Jin, Haoyi; Wu, Pingeng; Lv, Chengcheng; Zhang, Shouyi; Zhang, Yunchao; Li, Changqi; Gao, Ruxu; Shan, Guangyi; Bi, Huan; Chang, Hong; Liu, Xi; Zeng, Yu
肿瘤
表观遗传
肿瘤免疫
焦亡
乳酸化
细胞生物学
膀胱癌
免疫/内分泌
