Glioblastoma stem cells reprogram chromatin in vivo to generate selective therapeutic dependencies on DPY30 and phosphodiesterases
胶质母细胞瘤干细胞在体内重新编程染色质,以产生对 DPY30 和磷酸二酯酶的选择性治疗依赖性
期刊:Science Translational Medicine
影响因子:15.8
doi:10.1126/scitranslmed.abf3917
Deobrat Dixit, Briana C Prager, Ryan C Gimple, Tyler E Miller, Qiulian Wu, Shira Yomtoubian, Reilly L Kidwell, Deguan Lv, Linjie Zhao, Zhixin Qiu, Guoxin Zhang, Derrick Lee, Donglim Esther Park, Robert J Wechsler-Reya, Xiuxing Wang, Shideng Bao, Jeremy N Rich