The transcription factor RBPJ is required for inflammatory macrophage activation in thoracic aortic dissection by mediating mechanotransduction-induced glycolysis.
转录因子 RBPJ 通过介导机械转导诱导的糖酵解,在胸主动脉夹层中激活炎症巨噬细胞。
期刊:Cellular and Molecular Life Sciences
影响因子:6.2
doi:10.1007/s00018-025-05908-1
Yin Zhi-Qiang, Wen Ting, Cao Xiu-Li, Lv Zhao-Xia, Su Yang, Liang Liang, Zhang Pei-Ran, Yang Zi-Yan, Han Hua, Yan Xian-Chun, Zheng Qi-Jun
巨噬细胞
炎症
炎症/感染
信号转导
巨噬细胞
细胞生物学
免疫/内分泌