日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Concomitant targeting of FLT3 and BTK overcomes FLT3 inhibitor resistance in acute myeloid leukemia through the inhibition of autophagy.

通过抑制自噬,同时靶向 FLT3 和 BTK 可以克服急性髓系白血病中 FLT3 抑制剂的耐药性

Zhang Weiguo, Yu Guopan, Zhang Hongying, Basyal Mahesh, Ly Charlie, Yuan Bin, Ruvolo Vivian, Piya Sujan, Bhattacharya Seemana, Zhang Qi, Borthakur Gautam, Battula Venkata, Konopleva Marina, Rice William G, Andreeff Michael

The multi-kinase inhibitor CG-806 exerts anti-cancer activity against acute myeloid leukemia by co-targeting FLT3, BTK, and Aurora kinases

多激酶抑制剂CG-806通过共同靶向FLT3、BTK和Aurora激酶,发挥抗急性髓系白血病的活性。

Yu, Guopan; Zhang, Weiguo; Zhang, Hongying; Ly, Charlie; Basyal, Mahesh; Rice, William G; Andreeff, Michael

Combinatorial targeting of XPO1 and FLT3 exerts synergistic anti-leukemia effects through induction of differentiation and apoptosis in FLT3-mutated acute myeloid leukemias: from concept to clinical trial

XPO1 和 FLT3 联合靶向治疗通过诱导 FLT3 突变型急性髓系白血病细胞分化和凋亡发挥协同抗白血病作用:从概念到临床试验

Zhang, Weiguo; Ly, Charlie; Ishizawa, Jo; Mu, Hong; Ruvolo, Vivian; Shacham, Sharon; Daver, Naval; Andreeff, Michael