日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Proteasome inhibition triggers the formation of TRAIL receptor 2 platforms for caspase-8 activation that accumulate in the cytosol

蛋白酶体抑制会触发 TRAIL 受体 2 平台的形成,从而激活 caspase-8,并在细胞溶胶中积累

Christian T Hellwig, M Eugenia Delgado, Josip Skoko #, Lydia Dyck #, Carol Hanna, Alexa Wentges, Claudia Langlais, Cathrin Hagenlocher, Alexandra Mack, David Dinsdale, Kelvin Cain, Marion MacFarlane, Markus Rehm

Suppressive effects of the obese tumor microenvironment on CD8 T cell infiltration and effector function

肥胖肿瘤微环境对CD8 T细胞浸润和效应功能的抑制作用

Lydia Dyck ,Hannah Prendeville ,Mathilde Raverdeau ,Mieszko M Wilk ,Roisin M Loftus ,Aaron Douglas ,Janet McCormack ,Bruce Moran ,Michael Wilkinson ,Evanna L Mills ,Michael Doughty ,Aurelie Fabre ,Helen Heneghan ,Carel LeRoux ,Andrew Hogan ,Edward T Chouchani ,Donal O'Shea ,Donal Brennan ,Lydia Lynch

Distinct metabolic programs established in the thymus control effector functions of γδ T cell subsets in tumor microenvironments

胸腺中建立的独特代谢程序控制着肿瘤微环境中γδ T细胞亚群的效应功能。

Noella Lopes #,Claire McIntyre #,Stefania Martin #,Mathilde Raverdeau #,Nital Sumaria,Ayano C Kohlgruber,Gina J Fiala,Leandro Z Agudelo,Lydia Dyck,Harry Kane,Aaron Douglas,Stephen Cunningham,Hannah Prendeville,Roisin Loftus,Colleen Carmody,Philippe Pierre,Manolis Kellis,Michael Brenner,Rafael J Argüello,Bruno Silva-Santos #,Daniel J Pennington #,Lydia Lynch #

Metabolic reprogramming of natural killer cells in obesity limits antitumor responses

肥胖中自然杀伤细胞的代谢重编程限制了抗肿瘤反应

Xavier Michelet, Lydia Dyck, Andrew Hogan, Roisin M Loftus, Danielle Duquette, Kevin Wei, Semir Beyaz, Ali Tavakkoli, Cathriona Foley, Raymond Donnelly, Cliona O'Farrelly, Mathilde Raverdeau, Ashley Vernon, William Pettee, Donal O'Shea, Barbara S Nikolajczyk, Kingston H G Mills, Michael B Brenner, D

Pyruvate Kinase M2 Is Required for the Expression of the Immune Checkpoint PD-L1 in Immune Cells and Tumors

丙酮酸激酶 M2 是免疫细胞和肿瘤中免疫检查点 PD-L1 表达所必需的

Eva M Palsson-McDermott, Lydia Dyck, Zbigniew Zasłona, Deepthi Menon, Anne F McGettrick, Kingston H G Mills, Luke A O'Neill

Anti-PD-1 inhibits Foxp3+ Treg cell conversion and unleashes intratumoural effector T cells thereby enhancing the efficacy of a cancer vaccine in a mouse model

抗 PD-1 抑制 Foxp3+ Treg 细胞转化并释放肿瘤内效应 T 细胞,从而增强小鼠模型中癌症疫苗的功效

Lydia Dyck, Mieszko M Wilk, Mathilde Raverdeau, Alicja Misiak, Louis Boon, Kingston H G Mills

Tumor-derived microvesicles mediate human breast cancer invasion through differentially glycosylated EMMPRIN

肿瘤来源的微囊泡通过差异糖基化的EMMPRIN介导人乳腺癌侵袭

Kerstin Menck ,Christian Scharf ,Annalen Bleckmann ,Lydia Dyck ,Ulrike Rost ,Dirk Wenzel ,Vishnu M Dhople ,Laila Siam ,Tobias Pukrop ,Claudia Binder ,Florian Klemm

Blocking retinoic acid receptor-α enhances the efficacy of a dendritic cell vaccine against tumours by suppressing the induction of regulatory T cells

阻断视黄酸受体-α可通过抑制调节性 T 细胞的诱导来增强树突状细胞疫苗对抗肿瘤的功效

Karen C Galvin, Lydia Dyck, Neil A Marshall, Anna M Stefanska, Kevin P Walsh, Barry Moran, Sarah C Higgins, Lara S Dungan, Kingston H G Mills