日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

ERBB2 signaling drives immune cell evasion and resistance against immunotherapy in small cell lung cancer

ERBB2信号通路驱动小细胞肺癌中的免疫细胞逃逸和对免疫疗法的耐药性

Lydia Meder # ,Charlotte I Orschel # ,Cyrielle L Bouchez # ,Rahil Gholamipoorfard ,Claudia V Orschel ,David Stahl ,Christoph Kreer ,Mirjam Koker ,Marieke Nill ,Ilayda G Kocak ,Ka-Won Noh ,Xinlei Zhao ,Leon Ullrich ,Björn Häupl ,Josefine Jakob ,Marie-Lisa Eich ,Alexandra Florin ,Holger Grüll ,Jürgen Wolf ,Filippo Beleggia ,Reinhard Büttner ,Thomas Oellerich ,Florian Klein ,Johannes Brägelmann ,H Christian Reinhardt ,Nima Abedpour ,Roland T Ullrich

Blocking the angiopoietin-2-dependent integrin β-1 signaling axis abrogates small cell lung cancer invasion and metastasis

阻断血管生成素 2 依赖性整合素 β-1 信号轴可抑制小细胞肺癌的侵袭和转移

Lydia Meder, Charlotte Isabelle Orschel, Christoph Julius Otto, Mirjam Koker, Johannes Brägelmann, Meryem S Ercanoglu, Sabrina Dähling, Anik Compes, Carolin Selenz, Marieke Nill, Felix Dietlein, Alexandra Florin, Marie-Lisa Eich, Sven Borchmann, Margarete Odenthal, Raquel Blazquez, Frank Hilberg, Fl

Somatic rearrangements causing oncogenic ectodomain deletions of FGFR1 in squamous cell lung cancer

导致鳞状细胞肺癌中致癌 FGFR1 胞外域缺失的体细胞重排

Florian Malchers, Lucia Nogova, Martijn Ha van Attekum, Lukas Maas, Johannes Brägelmann, Christoph Bartenhagen, Luc Girard, Graziella Bosco, Ilona Dahmen, Sebastian Michels, Clare E Weeden, Andreas H Scheel, Lydia Meder, Kristina Golfmann, Philipp Schuldt, Janna Siemanowski, Jan Rehker, Sabine Merke

SQSTM1/p62 promotes miR-198 loading into extracellular vesicles and its autophagy-related secretion

SQSTM1/p62促进miR-198装载到细胞外囊泡及其自噬相关分泌

Xiaojie Yu, Hannah Eischeid-Scholz, Lydia Meder, Vangelis Kondylis, Reinhard Büttner, Margarete Odenthal

EGFR Inhibition Strongly Modulates the Tumour Immune Microenvironment in EGFR-Driven Non-Small-Cell Lung Cancer

EGFR 抑制强烈调节 EGFR 驱动的非小细胞肺癌中的肿瘤免疫微环境

Carolin Selenz, Anik Compes, Marieke Nill, Sven Borchmann, Margarete Odenthal, Alexandra Florin, Johannes Brägelmann, Reinhard Büttner, Lydia Meder, Roland T Ullrich

Trophoblast Cell Surface Antigen 2 (TROP2) as a Predictive Bio-Marker for the Therapeutic Efficacy of Sacituzumab Govitecan in Adenocarcinoma of the Esophagus

滋养层细胞表面抗原 2 (TROP2) 作为 Sacituzumab Govitecan 对食管腺癌治疗效果的预测生物标志物

Sascha Hoppe, Lydia Meder, Florian Gebauer, Roland T Ullrich, Thomas Zander, Axel M Hillmer, Reinhard Buettner, Patrick Plum, Julian Puppe, Wolfram Malter, Alexander Quaas

Pericentromeric Satellite III transcripts induce etoposide resistance

着丝粒周围卫星 III 转录本诱导依托泊苷抗性

Julian Kanne #, Michelle Hussong #, Jörg Isensee, Álvaro Muñoz-López, Jan Wolffgramm, Felix Heß, Christina Grimm, Sergey Bessonov, Lydia Meder, Jie Wang, H Christian Reinhardt, Margarete Odenthal, Tim Hucho, Reinhard Büttner, Daniel Summerer, Michal R Schweiger

Notch1 Deficiency Induces Tumor Cell Accumulation Inside the Bronchiolar Lumen and Increases TAZ Expression in an Autochthonous Kras LSL-G12V Driven Lung Cancer Mouse Model

Notch1 缺陷会诱导肿瘤细胞在支气管腔内积聚,并增加本土 Kras LSL-G12V 驱动的肺癌小鼠模型中的 TAZ 表达

Lydia Meder, Alexandra Florin, Luka Ozretić, Marieke Nill, Mirjam Koker, Sonja Meemboor, Freddy Radtke, Linda Diehl, Roland T Ullrich, Margarete Odenthal, Reinhard Büttner, Lukas C Heukamp

Inhibition of Tumor VEGFR2 Induces Serine 897 EphA2-Dependent Tumor Cell Invasion and Metastasis in NSCLC

抑制肿瘤 VEGFR2 可诱导 NSCLC 中丝氨酸 897 EphA2 依赖性肿瘤细胞侵袭和转移

Caroline Volz, Sara Breid, Carolin Selenz, Alina Zaplatina, Kristina Golfmann, Lydia Meder, Felix Dietlein, Sven Borchmann, Sampurna Chatterjee, Maike Siobal, Jakob Schöttle, Alexandra Florin, Mirjam Koker, Marieke Nill, Luka Ozretić, Niklas Uhlenbrock, Steven Smith, Reinhard Büttner, Hui Miao, Bing

Hepatic FTO is dispensable for the regulation of metabolism but counteracts HCC development in vivo

肝脏 FTO 对于代谢调节并非必不可少,但可抑制体内 HCC 的发展

Melanie J Mittenbühler, Katarzyna Saedler, Hendrik Nolte, Lara Kern, Jun Zhou, Shu-Bing Qian, Lydia Meder, Roland T Ullrich, Jens C Brüning, F Thomas Wunderlich