Structural basis for the synergy of 4'- and 2'-modifications on siRNA nuclease resistance, thermal stability and RNAi activity
4'-和2'-修饰对siRNA核酸酶抗性、热稳定性和RNAi活性协同作用的结构基础
期刊:Nucleic Acids Research
影响因子:16.6
doi:10.1093/nar/gky703
Joel M Harp, Dale C Guenther, Anna Bisbe, Lydia Perkins, Shigeo Matsuda, Gopal R Bommineni, Ivan Zlatev, Donald J Foster, Nate Taneja, Klaus Charisse, Martin A Maier, Kallanthottathil G Rajeev, Muthiah Manoharan, Martin Egli
