Lynch Jessica L相关文献与解析，生知库 | 链接生命科学的每一步

日期影响因子

Nonclinical toxicity study duration in AAV gene therapy development: Evidence from industry survey supports adequacy of short-term assessments

AAV基因治疗研发中非临床毒性研究的持续时间：行业调查证据支持短期评估的充分性

期刊:Molecular Therapy-Methods & Clinical Development

影响因子:4.7

doi:10.1016/j.omtm.2025.101628

Assaf, Basel T; Edwards, David; Berens, Shawn Jay; Lauritzen, Brian; Pierrot, Christelle; Tukov, Francis Fonyuy; Bertinetti-Lapatki, Cristina; Braun, Manuela; Schaefer, Kai; Lynch, Jessica L

发表日期：2025

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Regulatory Consideration for the Nonclinical Safety Assessment of Gene Therapies

基因疗法非临床安全性评估的监管考量

期刊:Human Gene Therapy

doi:10.1089/hum.2022.090

Moffit, Jeffrey S; Blanset, Diann L; Lynch, Jessica L; MacLachlan, Timothy K; Meyer, Kathleen E; Ponce, Rafael; Whiteley, Laurence O

发表日期：2022

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Nonclinical Studies that Support Viral Vector-Delivered Gene Therapies: An EFPIA Gene Therapy Working Group Perspective

支持病毒载体递送基因疗法的非临床研究：欧洲制药工业协会基因治疗工作组的观点

期刊:Molecular Therapy-Methods & Clinical Development

影响因子:4.7

doi:10.1016/j.omtm.2020.08.017

Bolt, Michael W; Whiteley, Laurence O; Lynch, Jessica L; Lauritzen, Brian; Fernández de Henestrosa, Antonio R; MacLachlan, Timothy; Ulrich, Peter; Philip, Binu K; Mahalingaiah, Prathap Kumar; Fuller, Claudette L; Compton, David R

发表日期：2020

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Reducing Risks and Delays in the Translation of Cell and Gene Therapy Innovations into Regulated Products

降低细胞和基因治疗创新成果转化为受监管产品过程中的风险和延误

doi:10.31478/201909d

Tsokas, Katherine; McFarland, Richard; Burke, Carl; Lynch, Jessica L; Bollenbach, Thomas; Callaway, D Allen 2nd; Siegel, Jay

细胞生物学

发表日期：2019

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Ovine proinflammatory cytokines cross the murine blood-brain barrier by a common saturable transport mechanism

绵羊促炎细胞因子通过一种常见的饱和转运机制穿过小鼠血脑屏障。

期刊:Neuroimmunomodulation

影响因子:2.4

doi:10.1159/000288265

Threlkeld, Steven W; Lynch, Jessica L; Lynch, Kristin M; Sadowska, Grazyna B; Banks, William A; Stonestreet, Barbara S

细胞生物学

免疫/内分泌

发表日期：2010

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Lipopolysaccharide alters the blood-brain barrier transport of amyloid beta protein: a mechanism for inflammation in the progression of Alzheimer's disease.

脂多糖改变血脑屏障对β-淀粉样蛋白的转运：这是阿尔茨海默病进展过程中炎症的一种机制

期刊:Brain Behavior and Immunity

影响因子:7.6

doi:10.1016/j.bbi.2009.01.017

Jaeger Laura B, Dohgu Shinya, Sultana Rukhsana, Lynch Jessica L, Owen Joshua B, Erickson Michelle A, Shah Gul N, Price Tulin O, Fleegal-Demotta Melissa A, Butterfield D Allan, Banks William A

免疫/内分泌

发表日期：2009

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Testing the neurovascular hypothesis of Alzheimer's disease: LRP-1 antisense reduces blood-brain barrier clearance, increases brain levels of amyloid-beta protein, and impairs cognition

检验阿尔茨海默病神经血管假说：LRP-1反义寡核苷酸降低血脑屏障清除率，增加脑内β-淀粉样蛋白水平，并损害认知功能

期刊:Journal of Alzheimers Disease

影响因子:3.1

doi:10.3233/JAD-2009-1074

Jaeger, Laura B; Dohgu, Shinya; Hwang, Mark C; Farr, Susan A; Murphy, M Paul; Fleegal-DeMotta, Melissa A; Lynch, Jessica L; Robinson, Sandra M; Niehoff, Michael L; Johnson, Steven N; Kumar, Vijaya B; Banks, William A

阿尔茨海默症

发表日期：2009

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Nitric oxide activity and isoenzyme expression in the senescence-accelerated mouse p8 model of Alzheimer's disease: effects of anti-amyloid antibody and antisense treatments

在衰老加速的阿尔茨海默病小鼠p8模型中，一氧化氮活性和同工酶表达：抗淀粉样蛋白抗体和反义治疗的影响

doi:10.1093/gerona/glp074

Ali, Abbas K; Banks, William A; Kumar, Vijaya B; Shah, Gul N; Lynch, Jessica L; Farr, Susan A; Fleegal-DeMotta, Melissa A; Morley, John E

阿尔茨海默症

发表日期：2009

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