日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Loss of DOT1L disrupts neuronal transcription and leads to a neurodevelopmental disorder

DOT1L 的缺失会扰乱神经元转录,并导致神经发育障碍。

Maroni, Marissa J; Barton, Melissa; Lynch, Katherine; Deshwar, Ashish R; Campbell, Philip D; Millard, Josephine; Lee, Rachel; Cohen, Annastelle; Ahmad, Rili; Paranjapye, Alekh; Faundes, Víctor; Repetto, Gabriela M; McKenna, Caoimhe; Shillington, Amelle L; Phornphutkul, Chanika; Hove, Hanne B; Mancini, Grazia M S; Schot, Rachel; Barakat, Tahsin Stefan; Richmond, Christopher M; Lauzon, Julie; Ibrahim, Ahmed Ibrahim Elsayed; Nava, Caroline; Héron, Delphine; van Aalst, Minke M A; Atemin, Slavena; Sleptsova, Mila; Aleksandrova, Iliyana; Todorova, Albena; Watkins, Debra L; Kozenko, Mariya A; Natera-de Benito, Daniel; Ortez, Carlos; Estevez-Arias, Berta; Lecoquierre, François; Cassinari, Kévin; Guerrot, Anne-Marie; Levy, Jonathan; Latypova, Xenia; Verloes, Alain; Innes, A Micheil; Yang, Xiao-Ru; Banka, Siddharth; Vill, Katharina; Jacob, Maureen; Kruer, Michael; Skidmore, Peter; Galaz-Montoya, Carolina I; Bakhtiari, Somayeh; Mester, Jessica L; Granato, Michael; Armache, Karim-Jean; Costain, Gregory; Korb, Erica

Histone variant H2BE enhances chromatin accessibility in neurons to promote synaptic gene expression and long-term memory

组蛋白变体H2BE增强神经元染色质的可及性,从而促进突触基因表达和长期记忆。

Feierman, Emily R; Louzon, Sean; Prescott, Nicholas A; Biaco, Tracy; Gao, Qingzeng; Qiu, Qi; Choi, Kyuhyun; Palozola, Katherine C; Voss, Anna J; Mehta, Shreya D; Quaye, Camille N; Lynch, Katherine T; Fuccillo, Marc V; Wu, Hao; David, Yael; Korb, Erica

Green Tea Catechins Decrease Solubility of Raloxifene In Vitro and Its Systemic Exposure in Mice.

绿茶儿茶素可降低雷洛昔芬在体外的溶解度及其在小鼠体内的全身暴露量

Oyanna Victoria O, Bechtold Baron J, Lynch Katherine D, Ridge Call M, Graf Tyler N, Oberlies Nicholas H, Clarke John D

Pharmacokinetic Effects of Different Models of Nonalcoholic Fatty Liver Disease in Transgenic Humanized OATP1B Mice

转基因人源化OATP1B小鼠不同非酒精性脂肪肝疾病模型的药代动力学效应

Bechtold, Baron J; Lynch, Katherine D; Oyanna, Victoria O; Call, M Ridge; White, Laura A; Graf, Tyler N; Oberlies, Nicholas H; Clarke, John D

Microcystin-LR activates serine/threonine kinases and alters the phosphoproteome in human HepaRG cells.

微囊藻毒素-LR 激活丝氨酸/苏氨酸激酶,改变人类 HepaRG 细胞的磷酸化蛋白质组

Ikumawoyi Victor O, Lynch Katherine D, Iverson Dayne T, Call M Ridge, Yue Guihua Eileen, Prasad Bhagwat, Clarke John D

Immune transgene-dependent myocarditis in macaques after systemic administration of adeno-associated virus expressing human acid alpha-glucosidase

系统性注射表达人类酸性α-葡萄糖苷酶的腺相关病毒后,恒河猴发生免疫转基因依赖性心肌炎

Juliette Hordeaux, Ali Ramezani, Steve Tuske, Nickita Mehta, Chunjuan Song, Anna Lynch, Katherine Lupino, Jessica A Chichester, Elizabeth L Buza, Cecilia Dyer, Hongwei Yu, Peter Bell, Jill M Weimer, Hung Do, James M Wilson

Goldenseal-Mediated Inhibition of Intestinal Uptake Transporters Decreases Metformin Systemic Exposure in Mice.

金印草介导的肠道吸收转运蛋白抑制作用降低了小鼠体内二甲双胍的全身暴露量

Oyanna Victoria O, Garcia-Torres Kenisha Y, Bechtold Baron J, Lynch Katherine D, Call M Ridge, Horváth Miklós, Manwill Preston K, Graf Tyler N, Cech Nadja B, Oberlies Nicholas H, Paine Mary F, Clarke John D

Identification, characterization and field testing of Brassica napus mutants producing high-oleic oils.

鉴定、表征和田间试验产生高油酸油的甘蓝型油菜突变体

Bai Shuangyi, Engelen Steven, Denolf Peter, Wallis James G, Lynch Katherine, Bengtsson Jesse D, Van Thournout Michel, Haesendonckx Boris, Browse John

Sodium modelling to reduce intradialytic hypotension during haemodialysis for acute kidney injury in the intensive care unit

在重症监护病房中,利用钠模型降低急性肾损伤血液透析过程中的透析中低血压发生率。

Lynch, Katherine E; Ghassemi, Fatimah; Flythe, Jennifer E; Feng, Mengling; Ghassemi, Marzyeh; Celi, Leo Anthony; Brunelli, Steven M

Association of mortality risk with various definitions of intradialytic hypotension

死亡风险与透析中低血压的不同定义之间的关联

Flythe, Jennifer E; Xue, Hui; Lynch, Katherine E; Curhan, Gary C; Brunelli, Steven M