日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Assessment of Spinster homologue 2 (Spns2)-dependent transport of sphingosine-1-phosphate as a therapeutic target.

评估 Spinster 同源物 2 (Spns2) 依赖的鞘氨醇-1-磷酸转运作为治疗靶点

Kharel Yugesh, Huang Tao, Dunnavant Kyle, Foster Daniel, Souza George M P R, Nimchuk Katherine E, Merchak Andrea R, Pavelec Caitlin M, Juskiewicz Zuzanna J, Alexander Simon S, Gaultier Alban, Abbott Stephen B G, Shin Jung-Bum, Isakson Brant E, Xu Wehao, Leitinger Norbert, Santos Webster L, Lynch Kevin R

Discovery of Potent, Orally Bioavailable Sphingosine-1-Phosphate Transporter (Spns2) Inhibitors

发现高效、口服生物利用度高的鞘氨醇-1-磷酸转运蛋白(Spns2)抑制剂

Foster, Daniel J; Dunnavant, Kyle; Shrader, Christopher W; LoPresti, Marion; Seay, Sarah; Kharel, Yugesh; Brown, Anne M; Huang, Tao; Lynch, Kevin R; Santos, Webster L

2-Aminobenzoxazole Derivatives as Potent Inhibitors of the Sphingosine-1-Phosphate Transporter Spinster Homolog 2 (Spns2)

2-氨基苯并恶唑衍生物作为鞘氨醇-1-磷酸转运蛋白Spinster同源物2 (Spns2) 的强效抑制剂

Burgio, Ariel L; Shrader, Christopher W; Kharel, Yugesh; Huang, Tao; Salamoun, Joseph M; Lynch, Kevin R; Santos, Webster L

Assay of Sphingosine 1-phosphate Transporter Spinster Homolog 2 (Spns2) Inhibitors

鞘氨醇-1-磷酸转运蛋白Spinster同源物2 (Spns2)抑制剂的测定

Kharel, Yugesh; Huang, Tao; Santos, Webster L; Lynch, Kevin R

Imidazole-based sphingosine-1-phosphate transporter Spns2 inhibitors

基于咪唑的鞘氨醇-1-磷酸转运蛋白Spns2抑制剂

Shrader, Christopher W; Foster, Daniel; Kharel, Yugesh; Huang, Tao; Lynch, Kevin R; Santos, Webster L

Discovery of In Vivo Active Sphingosine-1-phosphate Transporter (Spns2) Inhibitors

体内活性鞘氨醇-1-磷酸转运蛋白(Spns2)抑制剂的发现

Fritzemeier, Russell; Foster, Daniel; Peralta, Ashley; Payette, Michael; Kharel, Yugesh; Huang, Tao; Lynch, Kevin R; Santos, Webster L

A Novel Sphingosine Kinase Inhibitor Suppresses Chikungunya Virus Infection

一种新型鞘氨醇激酶抑制剂可抑制基孔肯雅病毒感染

Oyewole, Opeoluwa O; Dunnavant, Kyle; Bhattarai, Shaurav; Kharel, Yugesh; Lynch, Kevin R; Santos, Webster L; Reid, St Patrick

Photoacoustic microscopy reveals the hemodynamic basis of sphingosine 1-phosphate-induced neuroprotection against ischemic stroke

光声显微镜揭示了鞘氨醇-1-磷酸酯诱导的缺血性卒中神经保护作用的血流动力学基础

Cao, Rui; Li, Jun; Kharel, Yugesh; Zhang, Chenchu; Morris, Emily; Santos, Webster L; Lynch, Kevin R; Zuo, Zhiyi; Hu, Song

Increasing circulating sphingosine-1-phosphate attenuates lung injury during ex vivo lung perfusion

增加循环中的鞘氨醇-1-磷酸酯可减轻离体肺灌注过程中的肺损伤。

Mehaffey, J Hunter; Charles, Eric J; Narahari, Adishesh K; Schubert, Sarah; Laubach, Victor E; Teman, Nicholas R; Lynch, Kevin R; Kron, Irving L; Sharma, Ashish K

Correction: Mobilization studies in mice deficient in sphingosine kinase 2 support a crucial role of the plasma level of sphingosine-1-phosphate in the egress of hematopoietic stem progenitor cells

更正:在鞘氨醇激酶2缺陷小鼠中进行的动员研究表明,血浆中鞘氨醇-1-磷酸水平在造血干细胞祖细胞的迁移中起着至关重要的作用。

Adamiak, Mateusz; Chelvarajan, Lakshman; Lynch, Kevin R; Santos, Webster L; Abdel-Latif, Ahmed; Ratajczak, Mariusz Z