日期 影响因子
日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:
–

Deconvoluting drug interactions using M. tuberculosis physiologic processes: transcriptional disaggregation of the BPaL regimen in vivo

利用结核分枝杆菌生理过程解析药物相互作用：体内BPaL方案的转录解聚

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/aac.00492-25
Wynn, Elizabeth A; Dide-Agossou, Christian; Al Mubarak, Reem; Rossmassler, Karen; Hendrix, Jo; Voskuil, Martin I; Obregón-Henao, Andrés; Lyons, Michael A; Robertson, Gregory T; Moore, Camille M; Walter, Nicholas D
发表日期：2025
文献求助 收藏

Spectinamide MBX-4888A exhibits favorable lesion and tissue distribution and promotes treatment shortening in advanced murine models of tuberculosis

Spectinamide MBX-4888A 在晚期小鼠结核病模型中表现出良好的病灶和组织分布，并能缩短治疗时间。

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/aac.00716-24
Bauman, Allison A; Sarathy, Jansy P; Kaya, Firat; Massoudi, Lisa M; Scherman, Michael S; Hastings, Courtney; Liu, Jiuyu; Xie, Min; Brooks, Elizabeth J; Ramey, Michelle E; Jones, Isabelle L; Benedict, Noalani D; Maclaughlin, Madelyn R; Miller-Dawson, Jake A; Waidyarachchi, Samanthi L; Butler, Michelle M; Bowlin, Terry L; Zimmerman, Matthew D; Lenaerts, Anne J; Meibohm, Bernd; Gonzalez-Juarrero, Mercedes; Lyons, Michael A; Dartois, Veronique; Lee, Richard E; Robertson, Gregory T
发表日期：2024
文献求助 收藏

Pyrazinoic acid, the active form of the anti-tuberculosis drug pyrazinamide, and aromatic carboxylic acid analogs are protonophores

吡嗪酸（抗结核药物吡嗪酰胺的活性形式）和芳香族羧酸类似物是质子载体。

期刊:Frontiers in Molecular Biosciences
影响因子:4
doi:10.3389/fmolb.2024.1350699
Fontes, Fabio L; Rooker, Steven A; Lynn-Barbe, Jamie K; Lyons, Michael A; Crans, Debbie C; Crick, Dean C
发表日期：2024
文献求助 收藏

Standardized RS Ratio Metrics To Assess Tuberculosis Antimicrobial Efficacy and Potency

标准化RS比率指标用于评估结核病抗菌药物的疗效和效力

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/aac.01483-22
Reichlen, Matthew J; Born, Sarah E M; Lyons, Michael A; Rossmassler, Karen; Reid, Justin; Robertson, Gregory T; Walter, Nicholas D; Voskuil, Martin I
发表日期：2023
文献求助 收藏

Drug distribution and efficacy of the DprE1 inhibitor BTZ-043 in the C3HeB/FeJ mouse tuberculosis model.

DprE1抑制剂BTZ-043在C3HeB/FeJ小鼠结核病模型中的药物分布和疗效

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/aac.00597-23
Ramey Michelle E, Kaya Firat, Bauman Allison A, Massoudi Lisa M, Sarathy Jansy P, Zimmerman Matthew D, Scott Dashick W L, Job Alyx M, Miller-Dawson Jake A, Podell Brendan K, Lyons Michael A, Dartois Véronique, Lenaerts Anne J, Robertson Gregory T
其它
Mouse
药物研究
发表日期：2023
文献求助 收藏

Pharmacodynamics and Bactericidal Activity of Combination Regimens in Pulmonary Tuberculosis: Application to Bedaquiline-Pretomanid-Pyrazinamide

联合用药方案在肺结核治疗中的药效学和杀菌活性：以贝达喹啉-普瑞托马尼-吡嗪酰胺方案为例

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/aac.00898-22
Lyons, Michael A
微生物学
肺结核
发表日期：2022
文献求助 收藏

Pretomanid dose selection for pulmonary tuberculosis: An application of multi-objective optimization to dosage regimen design

普瑞托马尼治疗肺结核的剂量选择：多目标优化在给药方案设计中的应用

期刊:Cpt-Pharmacometrics & Systems Pharmacology
影响因子:3
doi:10.1002/psp4.12591
Lyons, Michael A
微生物学
肺结核
发表日期：2021
文献求助 收藏

Modeling and Simulation of Pretomanid Pharmacodynamics in Pulmonary Tuberculosis Patients

普瑞托马尼在肺结核患者中的药效学建模与仿真

期刊:Antimicrobial Agents and Chemotherapy
影响因子:4.5
doi:10.1128/AAC.00732-19
Lyons, Michael A
微生物学
肺结核
发表日期：2019
文献求助 收藏

Computational pharmacokinetics/pharmacodynamics of rifampin in a mouse tuberculosis infection model

利福平在小鼠结核感染模型中的计算药代动力学/药效学研究

期刊:Journal of Pharmacokinetics and Pharmacodynamics
影响因子:2.8
doi:10.1007/s10928-015-9419-z
Lyons, Michael A; Lenaerts, Anne J
炎症/感染
发表日期：2015
文献求助 收藏

Computational pharmacology of rifampin in mice: an application to dose optimization with conflicting objectives in tuberculosis treatment

利福平在小鼠体内的计算药理学：在结核病治疗中兼顾相互冲突的目标的剂量优化中的应用

期刊:Journal of Pharmacokinetics and Pharmacodynamics
影响因子:2.8
doi:10.1007/s10928-014-9380-2
Lyons, Michael A
发表日期：2014
文献求助 收藏