日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Proteolytic dissection of eIF4G reveals the closed-loop mRNP as an architecture for translation repression

对 eIF4G 进行蛋白水解分析揭示了闭环 mRNP 作为翻译抑制的结构。

Johnston, Ryan; Brekker, Mollie A; Khalil, Noelle; Goldstein, Monty E; Aldrich, Anne; Grimins, Autumn O; Gritli, Sami; Marintchev, Assen; Blower, Michael D; Saeed, Mohsan; Lyons, Shawn M

Decreased tRNA abundance contributes to decreased translation elongation rate in a prolonged mitosis.

tRNA 丰度降低会导致有丝分裂延长过程中翻译延伸速率降低。

Sparago Emily, Johnston Ryan, Lyons Shawn M, Blower Michael D

G-quadruplex topologies determine the functional outcome of guanine-rich bioactive oligonucleotides.

G-四链体拓扑结构决定了富含鸟嘌呤的生物活性寡核苷酸的功能结果

Kharel Prakash, Bhatter Nupur, Zubair Safiyah, Lyons Shawn M, Anderson Paul J, Ivanov Pavel

Amidino-rocaglates (ADRs), a class of synthetic rocaglates, are potent inhibitors of SARS-CoV-2 replication through inhibition of viral protein synthesis.

脒基罗卡格列酸酯(ADRs)是一类合成罗卡格列酸酯,可通过抑制病毒蛋白合成来有效抑制SARS-CoV-2复制

Keiser Patrick T, Zhang Wenhan, Ricca Michael, Wacquiez Alan, Grimins Autumn, Cencic Regina, Patten J J, Shah Pranav, Padilha Elias, Connor John H, Pelletier Jerry, Lyons Shawn M, Saeed Mohsan, Brown Lauren E, Porco John A Jr, Davey Robert A

Stress granule-mediated sequestration of EGR1 mRNAs correlates with lomustine-induced cell death prevention.

应激颗粒介导的 EGR1 mRNA 隔离与洛莫司汀诱导的细胞死亡预防相关

Leśniczak-Staszak Marta, Pietras Paulina, Ruciński Marcin, Johnston Ryan, Sowiński Mateusz, Andrzejewska Małgorzata, Nowicki Michał, Gowin Ewelina, Lyons Shawn M, Ivanov Pavel, Szaflarski Witold

The 3' Untranslated Regions of Ebola Virus mRNAs Contain AU-Rich Elements Involved in Posttranscriptional Stabilization and Decay

埃博拉病毒mRNA的3'非翻译区含有富含AU的元件,这些元件参与转录后稳定和降解过程。

Nelson, Emily V; Ross, Stephen J; Olejnik, Judith; Hume, Adam J; Deeney, Dylan J; King, Emily; Grimins, Autumn O; Lyons, Shawn M; Cifuentes, Daniel; Mühlberger, Elke

eIF4G has intrinsic G-quadruplex binding activity that is required for tiRNA function

eIF4G具有内在的G-四链体结合活性,这是tiRNA发挥功能所必需的。

Lyons, Shawn M; Kharel, Prakash; Akiyama, Yasutoshi; Ojha, Sandeep; Dave, Dhwani; Tsvetkov, Vladimir; Merrick, William; Ivanov, Pavel; Anderson, Paul

Revisiting the Concept of Stress in the Prognosis of Solid Tumors: A Role for Stress Granules Proteins?

重新审视实体瘤预后中的应激概念:应激颗粒蛋白的作用?

Aulas, Anaïs; Finetti, Pascal; Lyons, Shawn M; Bertucci, François; Birnbaum, Daniel; Acquaviva, Claire; Mamessier, Emilie

The role of RNA modifications in the regulation of tRNA cleavage

RNA修饰在tRNA切割调控中的作用

Lyons, Shawn M; Fay, Marta M; Ivanov, Pavel

A subset of replication-dependent histone mRNAs are expressed as polyadenylated RNAs in terminally differentiated tissues

在终末分化组织中,一部分复制依赖性组蛋白mRNA以多聚腺苷酸化RNA的形式表达。

Lyons, Shawn M; Cunningham, Clark H; Welch, Joshua D; Groh, Beezly; Guo, Andrew Y; Wei, Bruce; Whitfield, Michael L; Xiong, Yue; Marzluff, William F