日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Combinatorial immunotherapy drives exhaustion in tumor antigen-specific CD8+ T cells within the mouse renal tumor microenvironment.

联合免疫疗法导致小鼠肾肿瘤微环境中肿瘤抗原特异性 CD8+ T 细胞耗竭。

Stephens Holly R, Elkins Elizabeth, Li Jing, Swalley Zoey N, Ogbonna Henry Nnaemeka, Muri Pia, Roberts Zachary, Dempsey Francesca R, Ali Md Akkas, Siam Md Hasanul Banna, Kirkman Richard, Zhang Jianqing, Sudarshan Sunil, Tyrrell Daniel J, Tse Hubert M, Smith Daniel L Jr, Norian Lyse A

Granzyme B PET Imaging Predicts Response to Immunotherapy in a Diet-Induced Obesity Model of Breast Cancer.

颗粒酶 B PET 成像可预测饮食诱导肥胖乳腺癌模型对免疫疗法的反应

Lynch Shannon E, Crawford Corinne, Hunt Addison L, Sligh Luke L, Zhang Yujun, Norian Lyse A, Larimer Benjamin M, Lapi Suzanne E, Sorace Anna G

An Exogenous Ketone Ester Slows Tumor Progression in Murine Breast and Renal Cancer Models.

外源性酮酯可减缓小鼠乳腺癌和肾癌模型中的肿瘤进展。

Ogbonna Henry Nnaemeka, Roberts Zachary, Godwin Nicholas, Muri Pia, Turbitt William J, Swalley Zoey N, Dempsey Francesca R, Stephens Holly R, Zhang Jianqing, Plaisance Eric P, Norian Lyse A

Inhibition of the RNA Regulator HuR by SRI-42127 Attenuates Neuropathic Pain After Nerve Injury Through Suppression of Neuroinflammatory Responses

SRI-42127 抑制 RNA 调节因子 HuR,通过抑制神经炎症反应减轻神经损伤后的神经性疼痛

Robert E Sorge #, Ying Si #, Lyse A Norian, Abhishek Guha, Grace E Moore, L Burt Nabors, Natalia Filippova, Xiuhua Yang, Reed Smith, Rajeshwari Chellappan, Peter H King

Sequential modulation of the Wnt/β-catenin signaling pathway enhances tumor-intrinsic MHC I expression and tumor clearance

Wnt/β-catenin信号通路的顺序调控可增强肿瘤内在MHC I表达并促进肿瘤清除

Jhalak Dholakia ,Carly B Scalise ,Ashwini A Katre ,Whitney N Goldsberry ,Selene Meza-Perez ,Troy D Randall ,Lyse A Norian ,Lea Novak ,Rebecca C Arend

Re-Evaluating the Effects of Obesity on Cancer Immunotherapy Outcomes in Renal Cancer: What Do We Really Know?

重新评估肥胖对肾癌免疫疗法疗效的影响:我们究竟了解多少?

Farag, Kristine I; Makkouk, Amani; Norian, Lyse A

Neutralization of TGFβ Improves Tumor Immunity and Reduces Tumor Progression in Ovarian Carcinoma

TGFβ中和作用可改善肿瘤免疫力并减缓卵巢癌的肿瘤进展

Roane, Brandon M; Meza-Perez, Selene; Katre, Ashwini A; Goldsberry, Whitney N; Randall, Troy D; Norian, Lyse A; Birrer, Michael J; Arend, Rebecca C

Diabetes medications as potential calorie restriction mimetics-a focus on the alpha-glucosidase inhibitor acarbose

糖尿病药物作为潜在的热量限制模拟剂——以α-葡萄糖苷酶抑制剂阿卡波糖为例

Smith, Daniel L Jr; Orlandella, Rachael M; Allison, David B; Norian, Lyse A

Diet-Induced Obesity Impairs Outcomes and Induces Multi-Factorial Deficiencies in Effector T Cell Responses Following Anti-CTLA-4 Combinatorial Immunotherapy in Renal Tumor-Bearing Mice

饮食诱导的肥胖会损害肾肿瘤小鼠接受抗CTLA-4联合免疫疗法后的疗效,并导致效应T细胞反应的多因素缺陷

Turbitt, William J; Boi, Shannon K; Gibson, Justin T; Orlandella, Rachael M; Norian, Lyse A

Obesity diminishes response to PD-1-based immunotherapies in renal cancer

肥胖会降低肾癌患者对基于PD-1的免疫疗法的反应。

Boi, Shannon K; Orlandella, Rachael M; Gibson, Justin Tyler; Turbitt, William James; Wald, Gal; Thomas, Lewis; Buchta Rosean, Claire; Norris, Katlyn E; Bing, Megan; Bertrand, Laura; Gross, Brett P; Makkouk, Amani; Starenki, Dmytro; Farag, Kristine I; Sorge, Robert E; Brown, James A; Gordetsky, Jennifer; Yasin, Hesham; Garje, Rohan; Nandagopal, Lakshminarayanan; Weiner, George J; Lubaroff, David M; Arend, Rebecca C; Li, Peng; Zakharia, Yousef; Yang, Eddy; Salem, Aliasger K; Nepple, Kenneth; Marquez-Lago, Tatiana T; Norian, Lyse A