日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

The E. coli DnaX clamp loader sharply bends DNA to load β-clamp at nicks and small gaps.

大肠杆菌 DnaX 钳式装载器可使 DNA 急剧弯曲,从而在切口和小间隙处装载 β 钳。

Zheng Fengwei, Yao Nina Y, Georgescu Roxana E, Lyu Meinan, O'Donnell Michael E, Li Huilin

Pmt4 recognizes two separate acceptor sites to O-mannosylate in the S/T-rich regions of substrate proteins

Pmt4识别底物蛋白富含丝氨酸/胸苷酸(S/T)区域中的两个不同的O-甘露糖基化受体位点。

Du, Minge; Yuan, Zuanning; Kovach, Amanda; Lyu, Meinan; Li, Huilin

Elucidating the dynamics of integrin αIIbβ3 from native platelet membranes by cryo-EM with build-and-retrieve method

利用构建-回收法冷冻电镜阐明天然血小板膜中整合素αIIbβ3的动态变化

Han, Xu; Zhang, Zhemin; Su, Chih-Chia; Lyu, Meinan; Miyagi, Masaru; Yu, Edward; Nieman, Marvin T

Elucidating the dynamics of Integrin αIIbβ3 from native platelet membranes by cryo-EM with build and retrieve method

利用冷冻电镜构建和回收方法阐明天然血小板膜中整合素αIIbβ3的动态变化

Han, Xu; Zhang, Zhemin; Su, Chih-Chia; Lyu, Meinan; Miyagi, Masaru; Yu, Edward; Nieman, Marvin T

The Plasmodium falciparum NCR1 transporter is an antimalarial target that exports cholesterol from the parasite's plasma membrane.

恶性疟原虫 NCR1 转运蛋白是一种抗疟靶点,可将胆固醇从寄生虫的质膜中输出

Zhang Zhemin, Lyu Meinan, Han Xu, Bandara Sepalika, Cui Meng, Istvan Eva S, Geng Xinran, Tringides Marios L, Gregor William D, Miyagi Masaru, Oberstaller Jenna, Adams John H, Zhang Youwei, Nieman Marvin T, von Lintig Johannes, Goldberg Daniel E, Yu Edward W

Cryo-EM structures of the human band 3 transporter indicate a transport mechanism involving the coupled movement of chloride and bicarbonate ions

人带3转运蛋白的冷冻电镜结构表明,其转运机制涉及氯离子和碳酸氢根离子的偶联运动。

Su, Chih-Chia; Zhang, Zhemin; Lyu, Meinan; Cui, Meng; Yu, Edward W

Inhibition mechanism of NKCC1 involves the carboxyl terminus and long-range conformational coupling

NKCC1的抑制机制涉及羧基末端和长程构象偶联

Moseng, Mitchell A; Su, Chih-Chia; Rios, Kerri; Cui, Meng; Lyu, Meinan; Glaza, Przemyslaw; Klenotic, Philip A; Delpire, Eric; Yu, Edward W

Structural Basis of Peptide-Based Antimicrobial Inhibition of a Resistance-Nodulation-Cell Division Multidrug Efflux Pump

基于肽的抗菌药物抑制耐药性-结节形成-细胞分裂多药外排泵的结构基础

Lyu, Meinan; Ayala, Julio C; Chirakos, Isabella; Su, Chih-Chia; Shafer, William M; Yu, Edward W

Structures of the mycobacterial membrane protein MmpL3 reveal its mechanism of lipid transport

分枝杆菌膜蛋白MmpL3的结构揭示了其脂质转运机制。

Su, Chih-Chia; Klenotic, Philip A; Cui, Meng; Lyu, Meinan; Morgan, Christopher E; Yu, Edward W

Cryo-EM Structures of a Gonococcal Multidrug Efflux Pump Illuminate a Mechanism of Drug Recognition and Resistance

淋球菌多药外排泵的冷冻电镜结构揭示了药物识别和耐药机制。

Lyu, Meinan; Moseng, Mitchell A; Reimche, Jennifer L; Holley, Concerta L; Dhulipala, Vijaya; Su, Chih-Chia; Shafer, William M; Yu, Edward W