日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

Evolutionary divergence of the necroptosis effector MLKL

坏死凋亡效应因子 MLKL 的进化分歧

M C Tanzer, I Matti, J M Hildebrand, S N Young, A Wardak, A Tripaydonis, E J Petrie, A L Mildenhall, D L Vaux, J E Vince, P E Czabotar, J Silke, J M Murphy

HSP90 activity is required for MLKL oligomerisation and membrane translocation and the induction of necroptotic cell death

HSP90 活性是 MLKL 寡聚化和膜转位以及诱导坏死性细胞死亡所必需的

A V Jacobsen, K N Lowes, M C Tanzer, I S Lucet, J M Hildebrand, E J Petrie, M F van Delft, Z Liu, S A Conos, J-G Zhang, D C S Huang, J Silke, G Lessene, J M Murphy

Loss of PIDD limits NF-κB activation and cytokine production but not cell survival or transformation after DNA damage

PIDD的缺失会限制NF-κB的激活和细胞因子的产生,但不会影响DNA损伤后的细胞存活或转化。

F J Bock ,G Krumschnabel, C Manzl, L Peintner, M C Tanzer, N Hermann-Kleiter, G Baier, L Llacuna, J Yelamos, A Villunger

Death of p53-defective cells triggered by forced mitotic entry in the presence of DNA damage is not uniquely dependent on Caspase-2 or the PIDDosome

在 DNA 损伤的情况下,强制有丝分裂进入引发的 p53 缺陷细胞死亡并非仅仅依赖于 Caspase-2 或 PIDDosome

C Manzl, L L Fava, G Krumschnabel, L Peintner, M C Tanzer, C Soratroi, F J Bock, F Schuler, B Luef, S Geley, A Villunger