An EMT spectrum defines an anoikis-resistant and spheroidogenic intermediate mesenchymal state that is sensitive to e-cadherin restoration by a src-kinase inhibitor, saracatinib (AZD0530)
EMT 谱定义了一种抗细胞凋亡和球状体形成的中间间充质状态,该状态对 Src 激酶抑制剂萨拉卡替尼 (AZD0530) 修复 E-钙粘蛋白敏感
期刊:Cell Death & Disease
影响因子:8.1
doi:10.1038/cddis.2013.442
R Y-J Huang, M K Wong, T Z Tan, K T Kuay, A H C Ng, V Y Chung, Y-S Chu, N Matsumura, H-C Lai, Y F Lee, W-J Sim, C Chai, E Pietschmann, S Mori, J J H Low, M Choolani, J P Thiery
信号转导
细胞生物学
其它细胞
ELISA
Apoptosis