日期:
2020 年 — 2026 年
2020
2021
2022
2023
2024
2025
2026
影响因子:

HOXC10 Suppresses Browning to Maintain White Adipocyte Identity

HOXC10 抑制褐变以维持白色脂肪细胞身份

H Y Angeline Tan, M F Michelle Sim, Shi-Xiong Tan, Yvonne Ng, Sin Yee Gan, Hongyu Li, Suat Peng Neo, Jayantha Gunaratne, Feng Xu, Weiping Han

Oligomers of the lipodystrophy protein seipin may co-ordinate GPAT3 and AGPAT2 enzymes to facilitate adipocyte differentiation

脂肪营养障碍蛋白 seipin 的低聚物可能协调 GPAT3 和 AGPAT2 酶以促进脂肪细胞分化

M F Michelle Sim #, Elisa Persiani #, Md Mesbah Uddin Talukder, George D Mcilroy, Ahlima Roumane, J Michael Edwardson, Justin J Rochford

Discovering metabolic disease gene interactions by correlated effects on cellular morphology

通过对细胞形态的相关影响发现代谢疾病基因相互作用

Yang Jiao, Umer Ahmed, M F Michelle Sim, Andrea Bejar, Xiaolan Zhang, M Mesbah Uddin Talukder, Robert Rice, Jason Flannick, Anna I Podgornaia, Dermot F Reilly, Jesse M Engreitz, Maria Kost-Alimova, Kate Hartland, Josep-Maria Mercader, Sara Georges, Vilas Wagh, Marija Tadin-Strapps, John G Doench, J

Obesity-associated gene TMEM18 has a role in the central control of appetite and body weight regulation

与肥胖相关的基因TMEM18在中枢神经系统对食欲和体重的调控中发挥作用

Larder, Rachel; Sim, M F Michelle; Gulati, Pawan; Antrobus, Robin; Tung, Y C Loraine; Rimmington, Debra; Ayuso, Eduard; Polex-Wolf, Joseph; Lam, Brian Y H; Dias, Cristina; Logan, Darren W; Virtue, Sam; Bosch, Fatima; Yeo, Giles S H; Saudek, Vladimir; O'Rahilly, Stephen; Coll, Anthony P

Seipin oligomers can interact directly with AGPAT2 and lipin 1, physically scaffolding critical regulators of adipogenesis

Seipin 寡聚体可以直接与 AGPAT2 和脂质 1 相互作用,为脂肪生成的关键调节因子提供物理支架

Md Mesbah Uddin Talukder, M F Michelle Sim, Stephen O'Rahilly, J Michael Edwardson, Justin J Rochford

Intra-articular nodular fasciitis: an unexpected diagnosis for a joint lesion: a case report

关节内结节性筋膜炎:一种意想不到的关节病变诊断:病例报告

Chan, M F Michelle; Ong, K O; Foo, S S Leon; Selvarajan, S

Analysis of naturally occurring mutations in the human lipodystrophy protein seipin reveals multiple potential pathogenic mechanisms

对人类脂肪营养不良蛋白 seipin 自然突变的分析揭示了多种潜在的致病机制

M F Michelle Sim, M Mesbah Uddin Talukder, Rowena J Dennis, Stephen O'Rahilly, J Michael Edwardson, Justin J Rochford

The human lipodystrophy protein seipin is an ER membrane adaptor for the adipogenic PA phosphatase lipin 1

人类脂肪营养不良蛋白seipin是脂肪生成PA磷酸酶lipin 1的内质网膜衔接蛋白。

Sim, M F Michelle; Dennis, Rowena J; Aubry, Evelyne M; Ramanathan, Nardev; Sembongi, Hiroshi; Saudek, Vladimir; Ito, Daisuke; O'Rahilly, Stephen; Siniossoglou, Symeon; Rochford, Justin J