Valproic acid, an antiepileptic drug with histone deacetylase inhibitory activity, potentiates the cytotoxic effect of Apo2L/TRAIL on cultured thoracic cancer cells through mitochondria-dependent caspase activation

丙戊酸是一种具有组蛋白去乙酰化酶抑制活性的抗癫痫药物，它通过线粒体依赖性半胱天冬酶激活增强Apo2L/TRAIL对培养的胸部癌细胞的细胞毒性作用。