The androgen-regulated protease TMPRSS2 activates a proteolytic cascade involving components of the tumor microenvironment and promotes prostate cancer metastasis
雄激素调节蛋白酶TMPRSS2激活涉及肿瘤微环境成分的蛋白水解级联反应,并促进前列腺癌转移。
期刊:Cancer Discovery
影响因子:33.3
doi:10.1158/2159-8290.CD-13-1010
Lucas, Jared M; Heinlein, Cynthia; Kim, Tom; Hernandez, Susana A; Malik, Muzdah S; True, Lawrence D; Morrissey, Colm; Corey, Eva; Montgomery, Bruce; Mostaghel, Elahe; Clegg, Nigel; Coleman, Ilsa; Brown, Christopher M; Schneider, Eric L; Craik, Charles; Simon, Julian A; Bedalov, Antonio; Nelson, Peter S
肿瘤
肿瘤免疫
信号转导
前列腺癌
肿瘤微环境
免疫/内分泌