Novel insight into stem cell mobilization-plasma sphingosine-1-phosphate is a major chemoattractant that directs the egress of hematopoietic stem progenitor cells from the bone marrow and its level in peripheral blood increases during mobilization due to activation of complement cascade/membrane attack complex
对干细胞动员的新见解 - 血浆鞘氨醇-1-磷酸盐是一种主要的化学引诱剂,可引导造血干祖细胞从骨髓中流出,并且由于补体级联/膜攻击复合物的激活,其在动员过程中外周血中的水平会增加
期刊:Leukemia
影响因子:12.8
doi:10.1038/leu.2010.53
M Z Ratajczak, H Lee, M Wysoczynski, W Wan, W Marlicz, M J Laughlin, M Kucia, A Janowska-Wieczorek, J Ratajczak