Wogonin and related natural flavones are inhibitors of CDK9 that induce apoptosis in cancer cells by transcriptional suppression of Mcl-1
汉黄芩素和相关的天然黄酮是 CDK9 的抑制剂,可通过抑制 Mcl-1 的转录来诱导癌细胞凋亡
期刊:Cell Death & Disease
影响因子:8.1
doi:10.1038/cddis.2011.66
G Polier, J Ding, B V Konkimalla, D Eick, N Ribeiro, R Köhler, M Giaisi, T Efferth, L Desaubry, P H Krammer, M Li-Weber
信号转导
细胞生物学
肿瘤
肿瘤细胞
FCM
IF
IHC-P
Apoptosis
Human
BCL2